What dose escalation in the treatment of locally advanced non-small cell lung cancer?

被引：0
|
作者：
Thureau, S. [1 ,2 ,3 ]
Mallet, R. [1 ]
Gouel, P. [3 ]
Modzelewski, R. [2 ,3 ]
Vera, P. [2 ,3 ]
机构：
[1] Ctr Henri Becquerel, Dept radiotherapie & Phys med, Rouen, France
[2] Univ Rouen, Unite Quant LITIS EA 4108, Normandie, France
[3] Ctr Henri Becquerel, Dept imagerie, Rouen, France
来源：
CANCER RADIOTHERAPIE | 2022年 / 26卷 / 6-7期
关键词：
Lung radiotherapy; Escalation dose; PET; CONFORMAL RADIOTHERAPY; RADIATION-THERAPY; FDG PET; CHEMORADIOTHERAPY; RADIOCHEMOTHERAPY; MULTICENTER; CONCURRENT; VOLUME; NSCLC; PLAN;
D O I：
10.1016/j.canrad.2022.07.004
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Despite significant therapeutic advances in the treatment of locally advanced inoperable non-small cell lung cancer (NSCLC), notably through adjuvant immunotherapy, the rate of therapeutic failure remains high. The use of positron emission tomography with fluorodeoxyglucose (FDG-PET), respiratory motion and intensity modulated radiotherapy (IMRT) have led to therapeutic improvements with reduced toxicity and better local control. The optimal dose to be delivered remains unknown due to discordant results of studies for almost 20 years and the way to define the area to benefit from a dose increase (whole volume, subvolume defined by pre- or per-radiotherapy PET). (C) 2022 Published by Elsevier Masson SAS on behalf of Societe franc, aise de radiotherapie oncologique (SFRO).
引用
收藏
页码：890 / 893
页数：4
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