Effective dose of dual-energy X-ray absorptiometry scans in children as a function of age

被引:40
|
作者
Thomas, SR
Kalkwarf, HJ
Buckley, DD
Heubi, JE
机构
[1] Univ Cincinnati, Coll Med, Dept Radiol, Cincinnati, OH 45221 USA
[2] Childrens Hosp, Med Ctr, Div Gen & Community Pediat, Cincinnati, OH 45229 USA
[3] Childrens Hosp, Med Ctr, Gen Clin Res Ctr, Cincinnati, OH 45229 USA
基金
美国国家卫生研究院;
关键词
pediatric dosimetry; effective dose; radiation exposure; DXA; dual-energy X-ray absorptiometry; Hologic QDR 4500A;
D O I
10.1385/JCD:8:4:415
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Effective dose, a parameter utilized to assess biological risk related to radiation exposure. may be used to evaluate risk associated with dual-energy X-ray absorptionietry (DXA). We estimated the effective dose from DXA (Hologic QDR 4500A) scans of the lumbar spine (fast array mode), total body, hip (fast array mode), and forearm for children ages 1, 5, 10, and 15 yr and for adults. Entrance dose incorporating backscatter was determined for each scan type. Depth-dose curves were derived using Plexiglas stabs simulating tissue attenuation. Organ depth was estimated using pediatric phantom models. For all scan types, the effective dose decreased as age increased. The effective dose values for a 1-yr-old and an adult, respectively, were 4.7 mu Sv and 2.2 mu Sv for a lumbar spine scan performed in fast array mode, 3.4/3.5 mu Sv and 1.8/2.1 mu Sv (male/female) for a total body scan, and 0.14 mu Sv and 0.03 mu Sv for a forearm scan. There were marked sex differences in the effective dose associated with hip scans (fast array mode) ranging from 15.2 mu Sv for a 1-yr-old male to 4.6 mu Sv for an adult female. A comprehensive uncertainty analysis indicated that the effective dose values were reliable within a factor of 3. With the exception of the hip scans in 1- and 5-yr-olds, the effective doses were below the negligible individual dose limit of 10 mu Sv/yr.
引用
收藏
页码:415 / 422
页数:8
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