Electrospun nanofibers-based online micro-solid phase extraction for the determination of monohydroxy polycyclic aromatic hydrocarbons in human urine

被引:21
|
作者
Zhang, Huifang [1 ]
Xu, Hui [1 ]
机构
[1] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Hubei, Peoples R China
基金
中国国家自然科学基金;
关键词
Online micro-solid phase extraction; Electrospun nanofibers; Liquid chromatography-mass spectrometry; Silver nanoparticles; Monohydroxy polycyclic aromatic hydrocarbons; PERFORMANCE LIQUID-CHROMATOGRAPHY; MASS-SPECTROMETRY; FOOD SAMPLES; MICROEXTRACTION; TUBE; METABOLITES; CARBON; SILVER; NANOCOMPOSITE; ALDEHYDES;
D O I
10.1016/j.chroma.2017.09.035
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
In this article, silver nanoparticles (AgNPs) modified nanofibers that represent a novel kind of packing materials for micro-solid phase extraction (mu-SPE) is reported for the first time. The composite material was fabricated through in-situ formation of AgNPs on the polydopamine (PDA) coated polystyrene electrospun fibers (PS@PDA-Ag). The nanofibers displayed desirable hydrophilicity, large surface area, high porosity, good extraction ability and certain capacity to resist matrix interference. A mu-SPE combined with liquid chromatography-mass spectrometry (LC-MS) method was developed for the online determination of three monohydroxy polycyclic aromatic hydrocarbons (OH-PAHs) metabolites in human urine. Under the optimal conditions, good linearity (0.02-5 ng mL(-1)) was acquired with the correlation coefficients (R-2) being larger than 0.9962. Low limits of detection (0.007-0.032 ng mL(-1)) expressed the satisfactory sensitivity of the method. Moreover, the intraday relative standard deviation values lower than 9.7% and the recoveries among the range of 71-116% were obtained. In general, the online mu-SPE-LC-MS method had the features of simplicity, rapidity, sensitivity and automation, and it was expected to become a promising approach for the online analysis of trace OH-PAHs in complex biological samples. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:27 / 35
页数:9
相关论文
共 50 条
  • [1] Electrospun core-shell nanofibers as an adsorbent for on-line micro-solid phase extraction of monohydroxy derivatives of polycyclic aromatic hydrocarbons from human urine, and their quantitation by LC-MS
    Chen, Dan
    Xu, Hui
    [J]. MICROCHIMICA ACTA, 2020, 187 (01)
  • [2] Electrospun core-shell nanofibers as an adsorbent for on-line micro-solid phase extraction of monohydroxy derivatives of polycyclic aromatic hydrocarbons from human urine, and their quantitation by LC-MS
    Dan Chen
    Hui Xu
    [J]. Microchimica Acta, 2020, 187
  • [3] Portable micro-solid phase extraction for the determination of polycyclic aromatic hydrocarbons in water samples
    Abidin, Nurul Nabilah Zainal
    Sanagi, Mohd Marsin
    Ibrahim, Wan Aini Wan
    Endud, Salasiah
    Shukri, Dyia Syaleyana Md
    [J]. ANALYTICAL METHODS, 2014, 6 (15) : 5512 - 5518
  • [4] Magnetic molecularly imprinted polymers-silver nanoparticle based micro-solid phase extraction for the determination of polycyclic aromatic hydrocarbons in water samples
    Khajeh, Mostafa
    Sharifirad, Marzieh
    Bohlooli, Mousa
    Ghaffari-Moghaddam, Mansour
    [J]. RSC ADVANCES, 2016, 6 (60): : 54702 - 54708
  • [5] Quantification of selected monohydroxy metabolites of polycyclic aromatic hydrocarbons in human urine
    Liu, Libin
    Luo, Yueping
    Bi, Junping
    Li, Haifang
    Lin, Jin-Ming
    [J]. SCIENCE CHINA-CHEMISTRY, 2015, 58 (10) : 1579 - 1584
  • [6] Quantification of selected monohydroxy metabolites of polycyclic aromatic hydrocarbons in human urine
    Libin Liu
    Yueping Luo
    Junping Bi
    Haifang Li
    Jin-Ming Lin
    [J]. Science China Chemistry, 2015, 58 (10) : 1579 - 1584
  • [7] Quantification of selected monohydroxy metabolites of polycyclic aromatic hydrocarbons in human urine
    Libin Liu
    Yueping Luo
    Junping Bi
    Haifang Li
    JinMing Lin
    [J]. Science China(Chemistry), 2015, (10) - 1584
  • [8] Quantification of selected monohydroxy metabolites of polycyclic aromatic hydrocarbons in human urine
    Libin Liu
    Yueping Luo
    Junping Bi
    Haifang Li
    Jin-Ming Lin
    [J]. Science China Chemistry, 2015, 58 : 1579 - 1584
  • [9] Simultaneous Determination of Seven Metabolites of Polycyclic Aromatic Hydrocarbons in Human Urine by Online Solid Phase Extraction-High Performance Liquid Chromatography
    You Fan
    Zhu Lan
    He Ling
    Ran Liang-Ji
    Jin Yan
    Sun Cheng-Jun
    [J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2014, 42 (12) : 1723 - 1728
  • [10] Use of Polyetheretherketone as a Material for Solid Phase Extraction of Hydroxylated Metabolites of Polycyclic Aromatic Hydrocarbons in Human Urine
    Li, Xue
    Zenobi, Renato
    [J]. ANALYTICAL CHEMISTRY, 2013, 85 (07) : 3526 - 3531