Negative pressure wound therapy as an adjunct in healing of chronic wounds

被引:57
|
作者
Langer, Vijay [1 ]
Bhandari, Prem S. [1 ]
Rajagopalan, Satyamoorthy [2 ]
Mukherjee, Mrinal K. [1 ]
机构
[1] Army Hosp Res & Referral, Dept Plast & Reconstruct Surg, New Delhi 110010, India
[2] Armed Forces Med Coll, Dept Surg, Pune, Maharashtra, India
关键词
Chronic wounds; Negative pressure wound therapy; Vacuum sealing technique; Wound bed preparation; Wounds and injuries; VACUUM-ASSISTED CLOSURE; GLYCATION END-PRODUCTS; EXPERIENCE; DEVICE; TRIAL;
D O I
10.1111/iwj.12132
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Negative pressure wound therapy (NPWT) has emerged as a cutting-edge technology and provides an alternative solution to the problem of wounds. This study was undertaken to assess the efficacy of this technique in the treatment of chronic wounds. A prospective clinical study was used to evaluate our experience in use of NPWT in the healing of pressure ulcers and chronic wounds over 2 years. The primary end point of the study group was the time taken for appearance of healthy granulation tissue and full reepithelialisation without drainage. All patients with sepsis were excluded from the study. The statistical analysis of the data was carried out. Of the 60 patients studied, 41 had associated comorbidities including diabetes mellitus. The commonest site of occurrence was the lower limb. Coverage in the form of a flap was required at presentation in 6333% of patients. However, after initiation of NPWT, none of them required the procedure and they healed spontaneously either by secondary intention or by skin grafting. The time taken for appearance of healthy granulation tissue was 1436 +/- 424 days. Complete healing of wounds occurred by 331 +/- 1022 days. There was a statistically significant difference in the volume of the wounds before and after the intervention (P = 0000). Complications resulting from NPWT were minimal. This technique is an excellent adjunct to surgical debridement.
引用
收藏
页码:436 / 442
页数:7
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