Genetic immunization against the nonstructural proteins NS3, NS4 and NS5 of hepatitis C virus generates broad based cellular and humoral immune responses and protection in a tumor model.

被引：0
|
作者：
Encke, J [1 ]
Putlitz, JZ [1 ]
Geissler, M [1 ]
Wands, JR [1 ]
机构：
[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Mol Hepatol Lab, Charlestown, MA USA
来源：
HEPATOLOGY | 1998年 / 28卷 / 04期
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D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
1210
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页码：465A / 465A
页数：1
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  • [1] Generation and Characterization of Chimeric Antibodies against NS3, NS4, NS5, and Core Antigens of Hepatitis C Virus
    Tu, Bailin
    Ziemann, Robert N.
    Tieman, Bryan C.
    Hawksworth, David J.
    Tyner, Joan
    Scheffel, James
    Pinkus, Mary S.
    Brophy, Susan E.
    Werneke, Jeffrey M.
    Gutierrez, Robin
    White, Michael
    [J]. CLINICAL AND VACCINE IMMUNOLOGY, 2010, 17 (06) : 1040 - 1047
  • [2] Genetic immunization generates broad-based cellular and humoral immune responses against the nonstructural proteins of hepatitis C virus
    Encke, J
    Putlitz, JZ
    Geissler, M
    Wands, JR
    [J]. GASTROENTEROLOGY, 1998, 114 (04) : A1238 - A1238
  • [3] Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B
    Koch, JO
    Bartenschlager, R
    [J]. JOURNAL OF VIROLOGY, 1999, 73 (09) : 7138 - 7146
  • [4] Genetic immunization generates cellular and humoral immune responses against the nonstructural proteins of the hepatitis C virus in a murine model
    Encke, J
    Putlitz, JZ
    Geissler, M
    Wands, JR
    [J]. JOURNAL OF IMMUNOLOGY, 1998, 161 (09): : 4917 - 4923
  • [5] Ethanol inhibition: The humoral and cellular immune response to hepatitis C virus NS5 protein after genetic immunization
    Encke, J
    Wands, JR
    [J]. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2000, 24 (07) : 1063 - 1069
  • [6] Antigenic variation of core, NS3, and NS5 proteins among genotypes of hepatitis C virus
    Neville, JA
    Prescott, LE
    Bhattacherjee, V
    Adams, N
    Pike, I
    Rodgers, B
    ElZayadi, A
    Hamid, S
    Dusheiko, GM
    Saeed, AA
    Haydon, GH
    Simmonds, P
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (12) : 3062 - 3070
  • [7] Quantitative antibody responses to structural (core) and nonstructural (NS3, NS4, and NS5) hepatitis C virus proteins among seroconverting injecting drug users: Impact of epitope variation and relationship to detection of HCV RNA in blood
    Beld, M
    Penning, M
    van Putten, M
    Lukashov, V
    van den Hoek, A
    McMorrow, M
    Goudsmit, J
    [J]. HEPATOLOGY, 1999, 29 (04) : 1288 - 1298
  • [8] Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus
    Ishido, S
    Fujita, T
    Hotta, H
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998, 244 (01) : 35 - 40
  • [9] Evaluation of a Novel Enzyme-Linked Immuno Assay Model to Detect E2 Antigen and Antibodies Against Core, NS3, NS4, and NS5 Antigens of Hepatitis C Virus
    Kheirabad, Ali Kargar
    Nategh, Rakhshandeh
    Shokri, Fazel
    Pashabeyg, Kobra Razavi
    Norouzi, Mehdi
    [J]. HEPATITIS MONTHLY, 2020, 20 (09) : 1 - 7
  • [10] BOTH NS3 AND NS4A ARE REQUIRED FOR PROTEOLYTIC PROCESSING OF HEPATITIS-C VIRUS NONSTRUCTURAL PROTEINS
    FAILLA, C
    TOMEI, L
    DEFRANCESCO, R
    [J]. JOURNAL OF VIROLOGY, 1994, 68 (06) : 3753 - 3760
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