Liquid-phase biochemical sensing with disk-type resonant microsensor

被引：0
|
作者：
Seo, Jae Hyeong [1 ]
Betancor, Lorena [2 ]
Demirci, Kemal Safak [1 ]
Byun, Albert [1 ]
Spain, Jim [3 ]
Brand, Oliver [1 ]
机构：
[1] Georgia Inst Technol, Sch Elect & Comp Engn, Atlanta, GA 30332 USA
[2] Univ Cambridge, Dept Biochem, Cambridge, England
[3] Georgia Inst Technol, Sch Civil & Environm Engn, Atlanta, GA USA
来源：
TRANSDUCERS '07 & EUROSENSORS XXI, DIGEST OF TECHNICAL PAPERS, VOLS 1 AND 2 | 2007年
基金：
美国国家科学基金会;
关键词：
resonant sensor; mass-sensitive sensor; biosensor; beta-galactosidase enzyme;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
The application of a resonant microsensor platform based on disk-type microstructures vibrating in an in-plane resonance mode for biochemical sensing in liquid environment is described. Based on the measured short-term frequency stabilities of 1.1 10(-8) in air and 2.3 10(-6) in water, tow femtogram and sub-picogram detection limits can be achieved in air and in liquid, respectively. The feasibility of liquid-phase biosensing using the disk resonators is demonstrated experimentally by detecting anti-beta-galactosidase antibody using covalently immobilized beta-galactosidase enzyme.
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页数：2
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