Novel multicomponent reaction for the combinatorial synthesis of 2-imidazolines

被引：107
|
作者：
Bon, RS [1 ]
Hong, CG [1 ]
Bouma, MJ [1 ]
Schmitz, RF [1 ]
de Kanter, FJJ [1 ]
Lutz, M [1 ]
Spek, AL [1 ]
Orru, RVA [1 ]
机构：
[1] Free Univ Amsterdam, Dept Chem, NL-1081 HV Amsterdam, Netherlands
来源：
ORGANIC LETTERS | 2003年 / 5卷 / 20期
关键词：
D O I：
10.1021/ol035521g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The three-component condensation between an amine, an aldehyde, and an alpha-acidic isocyanide efficiently provides substituted 2-imidazolines in a one-pot reaction under mild conditions.
引用
收藏
页码：3759 / 3762
页数：4
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