Labeling of Hinokitiol with 90Y for Potential Radionuclide Therapy of Hepatocellular Carcinoma

被引：4

作者：

Bouvry, Christelle ^{[1
,2
]}

Ardisson, Valerie ^{[1
]}

Noiret, Nicolas ^{[3
]}

Garin, Etienne ^{[1
,4
]}

Lepareur, Nicolas ^{[1
,4
]}

机构：

[1] Comprehens Canc Ctr Eugene Marquis, F-35042 Rennes, France

[2] Univ Rennes, ISCR Inst Sci Chim Rennes UMR 6226, CNRS, F-35000 Rennes, France

[3] Univ Rennes, ISCR Inst Sci Chim Rennes UMR 6226, CNRS, ENSCR, F-35000 Rennes, France

[4] Univ Rennes, Inst NUMECAN Nutr Metabolismes & Canc UMR 1341, UMR S 1241, Inrae,Inserm, F-35033 Rennes, France

来源：

PROCESSES | 2021年 / 9卷 / 06期

关键词：

hepatocellular carcinoma; hinokitiol; lipiodol; radionuclide therapy; yttrium-90; TRANSARTERIAL RADIOEMBOLIZATION; RADIATION-EXPOSURE; METAL-COMPLEXES; POSSIBLE AGENT; TROPOLONE; LIPIODOL; CHELATE; OXINE; IONS; BIODISTRIBUTION;

D O I：

10.3390/pr9060940

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Hepatocellular carcinoma (HCC), the most common form of primary liver tumors, is the fifth cancer in the world in terms of incidence, and third in terms of mortality. Despite significant advances in the treatment of HCC, its prognosis remains bleak. Transarterial radioembolization with radiolabeled microspheres and Lipiodol has demonstrated significant effectiveness. Here we present a new, simple radiolabeling of Lipiodol with Yttrium-90, for the potential treatment of HCC.

引用

页数：14

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