Hepatopancreatobiliary surgery in a Mexican social security hospital during the COVID-19 pandemic

Introduction: Data on hepatopancreatobiliary (HPB) surgery and COVID-19 are scarce. The objective of the study was to determine the outcomes HPB procedures during the COVID-19 pandemic and compare results to the previous year. Methods: IRB approved study of HPB procedures (April, 2020-November, 2020). Primary endpoints: Thirty-day surgical morbidity/mortality, including COVID-19 infection. Secondary endpoints: Comparison between 2019 and 2020 procedures. Results: Twenty-five patients were included. In 2020, HPB procedures decreased 31.6%. About 60% developed complica-tions (Clavien-Dindo Grade III, 20%). Three patients developed post-operative COVID-19 infection (two deaths: 66% COVID-19 mortality). When compared to the previous year, there were more emergency cases, ventilator-assisted patients (p < 0.05) and pre-operative acute renal failure (p = 0.06). Clavien-Dindo complication grades were higher in 2020. Thirty-day mortality was also higher (16% vs. 5.6%). Conclusion: HPB surgical activity was negatively influenced by COVID-19 on 30-day mor-bidity/mortality. HPB patients who developed post-operative COVID-19 infection had a complicated course with significant mortality.