Fabrication of Polymersomes using Double-Emulsion Templates in Glass-Coated Stamped Microfluidic Devices

被引：87

作者：

Thiele, Julian ^{[1
,2
,3
]}

Abate, Adam R. ^{[1
,2
]}

Shum, Ho Cheung ^{[1
,2
]}

Bachtler, Simone ^{[1
,2
,4
]}

Foerster, Stephan ^{[3
]}

Weitz, David A. ^{[1
,2
]}

机构：

[1] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA

[2] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA

[3] Univ Hamburg, Inst Phys Chem, D-20146 Hamburg, Germany

[4] Univ Appl Sci, Hsch Mannheim, D-68163 Mannheim, Germany

来源：

SMALL | 2010年 / 6卷 / 16期

基金：

美国国家科学基金会;

关键词：

double emulsions; glass-coatings; PDMS microfluidics; polymersomes; MONODISPERSE DOUBLE EMULSIONS; BLOCK-COPOLYMER VESICLES; BIODEGRADABLE POLYMERSOMES; MULTIPLE EMULSIONS; POLY(DIMETHYLSILOXANE); PACLITAXEL; TUMORS; DRUG;

D O I：

10.1002/smll.201000798

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The formation of polymersomes from copolymer-stabilized double emulsions in glasscoated, PDMS microfluidic devices is described. The device geometry enables separate injection of two organic solvents to form the shell phase of the double emulsion. This allows proper combination of the two solvents, which is essential for forming polymersomes. © 2010 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim.

引用

下载

页码：1723 / 1727

页数：5

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