Giant Fold Gastritis Induced by Epoprostenol Infusion in Patients With Pulmonary Arterial Hypertension

被引：2
|
作者：
Miura, Yohei [1 ]
Kataoka, Masaharu [3 ]
Chiba, Tomohiro [2 ]
Inami, Takumi [1 ]
Yoshino, Hideaki [1 ]
Satoh, Toru [1 ]
机构：
[1] Kyorin Univ, Sch Med, Dept Internal Med 2, Div Cardiol, Tokyo, Japan
[2] Kyorin Univ, Sch Med, Dept Pathol, Tokyo, Japan
[3] Keio Univ, Sch Med, Dept Cardiol, Tokyo, Japan
来源：
CIRCULATION JOURNAL | 2018年 / 82卷 / 10期
关键词：
Epoprostenol; Giant fold gastritis; Pulmonary arterial hypertension; Stomach barium examination; THERAPY;
D O I：
10.1253/circj.CJ-18-0349
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background: Epoprostenol infusion is the strongest and most convincing therapeutic strategy for severe pulmonary arterial hypertension (PAH). This study investigated the gastrointestinal side effects of epoprostenol. Methods and Results: The study group of 12 patients treated with epoprostenol (epoprostenol group) and 4 patients without epoprostenol (control group) underwent stomach barium examination, which revealed that the prevalence of giant fold gastritis was significantly higher in the patients treated with epoprostenol (75% in epoprostenol group vs. 0% in control group; P=0.019). Conclusions: Giant fold gastritis may be an important side effect of epoprostenol infusion.
引用
收藏
页码：2676 / 2677
页数：2
相关论文
共 50 条
  • [1] Epoprostenol in pulmonary arterial hypertension
    Jacobs, Wouter
    Vonk-Noordegraaf, Anton
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2009, 5 (01) : 83 - 90
  • [2] Epoprostenol infusion therapy changes angiographic findings of pulmonary arteries in patients with idiopathic pulmonary arterial hypertension
    Sakuma, Masahito
    Demachi, Jun
    Nawata, Jun
    Suzuki, Jun
    Takahashi, Tohru
    Matsubara, Hiromi
    Akagi, Satoshi
    Shirato, Kunio
    CIRCULATION JOURNAL, 2008, 72 (07) : 1147 - 1151
  • [3] Rapid Initiation of Intravenous Epoprostenol Infusion Is the Favored Option in Patients with Advanced Pulmonary Arterial Hypertension
    Kimura, Mai
    Tamura, Yuichi
    Takei, Makoto
    Yamamoto, Tsunehisa
    Ono, Tomohiko
    Kuwana, Masataka
    Fukuda, Keiichi
    Satoh, Toru
    PLOS ONE, 2015, 10 (04):
  • [4] A comparison of rapid and slow initiation of intravenous epoprostenol infusion in patients with advanced pulmonary arterial hypertension
    Kimura, M.
    Tamura, Y.
    Yamamoto, T.
    Takei, M.
    Kataoka, M.
    Kawakami, T.
    Kuwana, M.
    Sano, M.
    Satoh, T.
    Fukuda, K.
    EUROPEAN HEART JOURNAL, 2014, 35 : 77 - 78
  • [5] Rapid Initiation of Intravenous Epoprostenol Infusion is the Favored Option in Patients with Advanced Pulmonary Arterial Hypertension
    Kimura, Mai
    Tamura, Yuichi
    Takei, Makoto
    Yamamoto, Tsunehisa
    Ono, Tomohiko
    Kawakami, Takashi
    Kataoka, Masaharu
    Kuwana, Masataka
    Satoh, Toru
    Fukuda, Keiichi
    JOURNAL OF CARDIAC FAILURE, 2014, 20 (10) : S163 - S163
  • [6] Epoprostenol Therapy for Pulmonary Arterial Hypertension
    Akagi, Satoshi
    Nakamura, Kazufumi
    Matsubara, Hiromi
    Ogawa, Aiko
    Sarashina, Toshihiro
    Ejiri, Kentaro
    Ito, Hiroshi
    ACTA MEDICA OKAYAMA, 2015, 69 (03) : 129 - 136
  • [7] Epoprostenol for the treatment of pulmonary arterial hypertension
    Cristo Ropero, Maria Jose
    Cruz-Utrilla, Alejandro
    Pilar Escribano-Subias, Maria
    EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 2021, 14 (08) : 1005 - 1013
  • [8] Endothelin-1 Across the Lung Circulation in Patients With Pulmonary Arterial Hypertension and Influence of Epoprostenol Infusion
    Selimovic, Nedim
    Andersson, Bert
    Bergh, Claes-Hakan
    Sakiniene, Egidija
    Carlsten, Hans
    Rundqvist, Bengt
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2009, 28 (08): : 808 - 814
  • [9] Effects and problems of continuous infusion of epoprostenol for patients with primary pulmonary hypertension
    Takahashi, T
    Sakuma, M
    Ikeda, J
    Nawata, J
    Demachi, J
    Kitamukai, O
    Shirato, K
    INTERNAL MEDICINE, 2002, 41 (10) : 784 - 788
  • [10] The experiences of patients with pulmonary. arterial hypertension receiving continuous intravenous infusion of epoprostenol (Flolan) and their support persons
    Hall, Heather
    Cote, Joanne
    McBean, Althea
    Purden, Margaret
    HEART & LUNG, 2012, 41 (01): : 35 - 43
12345