Postnatal weight change is influenced by mother-newborn pair leptin levels

被引:1
|
作者
Perrone, L [1 ]
Giuffrè, M [1 ]
D'Alfonso, C [1 ]
Carbone, MT [1 ]
Presta, G [1 ]
Di Toro, A [1 ]
Di Toro, R [1 ]
机构
[1] Univ Naples 2, Dept Paediat, I-80138 Naples, Italy
关键词
cord leptin level; postnatal weight loss; neonatal growth factor;
D O I
10.1016/S0271-5317(00)00237-2
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
We investigated serum leptin levels in 103 mother-newborn-pairs; Cord leptin was significantly higher than mother's leptin (5.7 +/- 5.5 vs. 22.1 +/- 19.9 ng/ml; p < 0.001). Cord leptin was significantly higher in females than males (6.9 <plus/minus> 6.3 vs. 3.9 +/- 3.6 ng/ml respectively; p < 0.001), and correlated with maternal leptin (r = 0.24; p = 0.001), gestational age (r = 8.54; p < 0.001), and birth weight (r = 0.56; p < 0.001). Neonatal leptin at the 4th day significantly correlated with percent weight loss in the first four days of life. These observations shed light on the origin of cord leptin and on the role of leptin in postnatal weight loss. (C) 2000 Elsevier Science Inc.
引用
收藏
页码:1531 / 1536
页数:6
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