EFFICIENT ONE-POT SYNTHESIS OF BENZO[e]PYRAZOLO-[1,5-c][1,3]THIAZINE DERIVATIVES UNDER COPPER-CATALYZED CONDITIONS

被引：6

作者：

Jie, Jiyang ^{[1
]}

Li, Haoyi ^{[1
]}

Piao, Meihui ^{[1
]}

Yang, Xiaobo ^{[1
]}

机构：

[1] Shenyang Normal Univ, Coll Chem & Chem Engn, Shenyang 110034, Liaoning, Peoples R China

来源：

HETEROCYCLES | 2016年 / 92卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Copper Catalyst; One-Pot Reaction; S-Arylation Reaction; Pyrazole; Thiazine; DIRECT IMINE ACYLATION; HETEROCYCLIC SCAFFOLDS; ACID-DERIVATIVES; CYCLIZATION; SCOPE;

D O I：

10.3987/COM-16-13477

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient method has been developed for the synthesis of benzo[e]pyrazolo[1,5-c][1,3]thiazines via one-pot two-step reactions of readily available substituted 1-(2-halopheny1)-3-akylprop-2-yn-1-ones, hydrazine hydrochloride and beta-oxodithioesters under mild conditions, and the corresponding benzo[e]pyrazolo[1,5-c][1,3]thiazines were obtained in good to excellent yields. The novel method affords a new strategy for the construction of diverse and useful poly N, S-heterocyclic compounds.

引用

页码：1215 / 1223

页数：9

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