Bidirectional Glenn shunt surgery using lepirudin anticoagulation in an infant with heparin-induced thrombocytopenia with thrombosis

被引：4
|
作者：
Iannoli, ED [1 ]
Eaton, MP [1 ]
Shapiro, JR [1 ]
机构：
[1] Univ Rochester, Sch Med & Dent, Dept Anesthesiol, Rochester, NY USA
来源：
ANESTHESIA AND ANALGESIA | 2005年 / 101卷 / 01期
关键词：
D O I：
10.1213/01.ANE.0000153019.15297.0B
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
There are few reports of the management of pediatric patients with heparin-induced thrombocytopenia (HIT) requiring cardiac surgery using currently available anticoagulants. We report a case of an infant with HIT requiring a bidirectional Glenn shunt who was successfully managed using lepirudin (r-hirudin, Refludan; Aventis, Bridgewater, NJ). Dosing and monitoring of anticoagulation were difficult, and we suggest caution in the use of lepirudin for cardiac surgery unless reliable monitoring of the degree of anticoagulation becomes available.
引用
收藏
页码：74 / 76
页数：3
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