Which treatment for nonalcoholic fatty liver disease?

被引：9
|
作者：
Moscatiello, S.
Marzocchi, R.
Villanova, N.
Bugianesi, E.
Marchesini, G. [1 ]
机构：
[1] Alma Mater Studiorum Univ Bologna, Policlin S Orsola, Unit Clin Dietet, I-40138 Bologna, Italy
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2008年 / 8卷 / 08期
关键词：
D O I：
10.2174/138955708784912193
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Subjects with nonalcoholic fatty liver disease are at risk of progressive liver failure. Lifestyle changes including weight-loss strategies and increased physical activity remain the first-line approach, but a few pharmacological treatments have also been successfully tested. Several drugs improve biochemistry, only a few improve histology; in all cases, the results were not sustained after treatment stop. Pharmacological treatment is not so far indicated outside controlled clinical trials with histological outcomes.
引用
收藏
页码：767 / 775
页数：9
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