Impact of age on elderly patients with oral cancer

IntroductionIn this study we have tried to analyze the impact of age on various clinico-pathological parameters, treatment completion and subsequent survival in older patients.Materials and methodsThis is a retrospective analysis of 140 elderly (>65years) patients of oral cancer operated between January 2012 and December 2013. The patients were divided into two groups based upon their age that 70years and >70years.Association of distribution of various clinico-pathological factors between different groups was assessed by using Chi-square test. Survival analysis was done using Kaplan Meir analysis. Univariate and multivariate analysis were performed.ResultsThe two groups had similar distribution of various clinico-pathological factors. Disease free survival for the group70 and >70years was 37.6months and 36.4months (p<0.594). 13.5% and 7.8% patients>70years and 70years were either advised or received sub-optimal adjuvant therapy (p<0.002).ConclusionThere is no difference distribution of various clinico-pathological factors and survival in patients of oral cancer 70 and>70years of age. Age did not affect survival. Majority of patients could complete the adjuvant therapy advised. Still, significantly more number of patients >70years could not receive/complete appropriate adjuvant therapy. Thus treatment needs to be tailored keeping in mind the individual's performance status and the co-morbidities.