Pharmaceutical and drug delivery applications of chitosan biopolymer and its modified nanocomposite: A review

被引：39
|
作者：
Kedir, Welela Meka [1 ]
Abdi, Gamachu Fikadu [1 ]
Goro, Meta Mamo [1 ]
Tolesa, Leta Deressa [1 ]
机构：
[1] Mettu Univ, Coll Nat & Computat Sci, Dept Chem, Mettu, Ethiopia
来源：
HELIYON | 2022年 / 8卷 / 08期
关键词：
Chitosan; Biopolymer; Nanocomposite; Pharmaceutical; Drug delivery; NANOPARTICLES; FORMULATION; TOXICITY; SYSTEMS; PECTIN; CLAY; POLYSACCHARIDE; ANTIBACTERIAL; DERIVATIVES; ABSORPTION;
D O I：
10.1016/j.heliyon.2022.e10196
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Due to their improved structural and functional properties as well as biocompatibility, biodegradability, and nontoxicity, chitosan and its nanoparticles are currently grasping the interest of researchers. Although numerous attempts have been made to apply chitosan and its derivatives to biological applications, few have reported in achieving its pharmacological and drug delivery. The goal of the current work is to provide a summary of the chitosan biopolymer's physical, chemical, and biological properties as well as its synthesis of nanoparticles and characterization of its modified nanocomposites. The drug delivery method and pharmaceutical applications of chitosan biopolymer and its modified nanocomposites are examined in further detail in this research. We will introduce also about the most current publications in this field of study as well as its recent expansion.
引用
收藏
页数：10
相关论文
共 50 条
  • [1] Chitosan: A Potential Biopolymer in Drug Delivery and Biomedical Applications
    Desai, Nimeet
    Rana, Dhwani
    Salave, Sagar
    Gupta, Raghav
    Patel, Pranav
    Karunakaran, Bharathi
    Sharma, Amit
    Giri, Jyotsnendu
    Benival, Derajram
    Kommineni, Nagavendra
    [J]. PHARMACEUTICS, 2023, 15 (04)
  • [2] Pharmaceutical and drug delivery applications of pectin and its modified nanocomposites
    Kedir, Welela Meka
    Deresa, Ebisa Mirete
    Diriba, Tamiru Fayisa
    [J]. HELIYON, 2022, 8 (09)
  • [3] Chitosan: A Propitious Biopolymer for Drug Delivery
    Duttagupta, Dibyangana S.
    Jadhav, Varsha M.
    Kadam, Vilasrao J.
    [J]. CURRENT DRUG DELIVERY, 2015, 12 (04) : 369 - 381
  • [4] Drug delivery applications of chitin and chitosan: a review
    Parhi, Rabinarayan
    [J]. ENVIRONMENTAL CHEMISTRY LETTERS, 2020, 18 (03) : 577 - 594
  • [5] Trimethyl chitosan and its applications in drug delivery
    Mourya, V. K.
    Inamdar, Nazma N.
    [J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2009, 20 (05) : 1057 - 1079
  • [6] Trimethyl chitosan and its applications in drug delivery
    V. K. Mourya
    Nazma N. Inamdar
    [J]. Journal of Materials Science: Materials in Medicine, 2009, 20
  • [7] Drug delivery applications of chitin and chitosan: a review
    Rabinarayan Parhi
    [J]. Environmental Chemistry Letters, 2020, 18 : 577 - 594
  • [8] A review on chitosan and its nanocomposites in drug delivery
    Ali, Akbar
    Ahmed, Shakeel
    [J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 109 : 273 - 286
  • [9] Pharmaceutical chitosan hydrogels: A review on its design and applications
    Chellathurai, Melbha Starlin
    Chung, Lip Yong
    Hilles, Ayah R.
    Sofian, Zarif Mohamed
    Singha, Souvik
    Ghosal, Kajal
    Mahmood, Syed
    [J]. International Journal of Biological Macromolecules, 2024, 280
  • [10] An Extensive Review on Hydrogels in Pharmaceutical Drug Delivery Applications
    Rajaram, Subashini
    Dharmalingam, Senthil Rajan
    Natarajan, Vignesh
    Ravi, Kaveena
    Shanmugam, Nivetha
    Somasundaram, Subbhashini Maruthamuthu
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION, 2022, 12 (02) : 108 - 112
12345