Micellar Catalysis in Fischer Glycosidation: En Route to Diverse Functional Glycosides

We have demonstrated that direct Fischer glycosidation of carbohydrates with selected alcohols, glycols and chloroalcohols to corresponding glucosides in micellar reaction system can be a promising and effective route for the selective synthesis of a number of functional glucosides. The use of specific catalyst combining both surfactant and acid catalyst functions enables formation of the reactive micellar system. The formation of corresponding glucosides with spectacular high selectivity to monoglucosides is one of the most important phenomena of the application of micellar catalysis to functional glucosides synthesis.