Copper-catalyzed enantioselective conjugate addition of triethylaluminum to 2-cyclopentenone

被引：28
|
作者：
Su, LM [1 ]
Li, XS [1 ]
Chan, WL [1 ]
Jia, X [1 ]
Chan, ASC [1 ]
机构：
[1] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Peoples R China
来源：
TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 13期
关键词：
D O I：
10.1016/S0957-4166(03)00349-5
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Bidentate phosphites were prepared starting from BINOL, H-8-BINOL or 3,3', 5,5'-tetra-tert-butyl-2,2'-biphenol. Utilization of these ligands in the copper-catalyzed enantioselective conjugate addition of triethylaluminum to 2-cyclopentenone afforded 3-ethylcyclopentanone in up to 94.0% ee. (C) 2003 Elsevier Science Ltd. All rights reserved.
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收藏
页码：1865 / 1869
页数：5
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