Lentzea tibetensis sp. nov., a novel Actinobacterium with antimicrobial activity isolated from soil of the Qinghai-Tibet Plateau

A novel filamentous Actinobacterium, designated strain FXJ1.1311(T), was isolated from soil collected in Ngari (Ali) Prefecture, Qinghai-Tibet Plateau, western PR China. The strain showed antimicrobial activity against Gram-positive bacteria and Fusarium oxysporum. Results of phylogenetic analysis based on 165 rRNA gene sequences indicated that strain FXJ1.1311(T) belonged to the genus Lentzea and showed the highest sequence similarity to Lentzea guizhouensis DHS C013(T) (98.04%). Morphological and chemotaxonomic characteristics supported its assignment to the genus Lentzea. The genome-wide average nucleotide identity between strain FXJ1.1311(T) and L. guizhouensis DHS C013(T) as well as other Lentzea type strains was <82.2%. Strain FXJ1.1311(T) also formed a monophyletic line distinct from the known Lentzea species in the phylogenomic tree. In addition, physiological and chemotaxonomic characteristics allowed phenotypic differentiation of the novel strain from L. guizhouensis. Based on the evidence presented here, strain FXJ1.1311(T) represents a novel species of the genus Lentzea, for which the name Lentzea tibetensis sp. nov. is proposed. The type strain is FXJ1.1311(T) (=CGMCC 4.7383(T) =DSM 104975(T)).