Amides Activation: Transition Metal-Free Coupling Between C-N Activated Amides and Enolizable Amides

被引：18

作者：

Joseph, Devaneyan ^{[1
]}

Oh, Min Seok ^{[1
]}

Jayaraman, Aravindan ^{[1
]}

Lee, Sunwoo ^{[1
]}

机构：

[1] Chonnam Natl Univ, Dept Chem, Gwangju 61186, South Korea

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2021年 / 42卷 / 10期

关键词：

Amide; Metal-free; Coupling; Condensation; beta-Ketoamide; H BOND-CLEAVAGE; CATALYZED TRANSAMIDATION; EFFICIENT CATALYST; CARBOXAMIDES; KETONES;

D O I：

10.1002/bkcs.12371

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Transition metal-free Claisen-type condensation between two different amides was developed. N-phenyl-N-tosylbenzamide derivatives reacted with enolizable amides such as N-methyl pyrrolidinone and N,N-dimethyl acetamide in the presence of NaHMDS to give their corresponding beta-ketoamides with moderate-to-good yields.

引用

页码：1293 / 1295

页数：3

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