Strong silver-silver interactions in three silver(I) carboxylate complexes with high cytotoxicity properties

Three carboxylate silver( I) complexes, [ Ag(fbc)]n, ( 1), [ Ag2(cpd)]n ( 2) and [Ag2(idc)]n ( 3), were prepared and characterized by X-ray single crystal analysis, where fbcH is 4-fluorobenzoic acid, cpdH2 is cyclopentane-1,1-dicarboxylic acid and idcH2 is iminodiacetic acid. The three coordination polymers show clear Ag-Ag bonds in their structures. The Ag-Ag bond length 2.850 angstrom both in 1 and 2 is much shorter than that ( 2.89 angstrom ) in metal silver, which is the shortest silver-silver interaction reported. The result of cytotoxicity of the three complexes indicates that they have very high crytotoxicity properties to normal cells and carcinoma cells.