Discovery of quality control markers from traditional Chinese medicines by fingerprint-efficacy modeling: Current status and future perspectives

被引：73
|
作者：
Zhang, Cai [1 ]
Zheng, Xian [1 ]
Ni, Hui [1 ]
Li, Ping [1 ]
Li, Hui-Jun [1 ]
机构：
[1] China Pharmaceut Univ, State Key Lab Nat Med, 24 Tongjia Lane, Nanjing 210009, Jiangsu, Peoples R China
来源：
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2018年 / 159卷
基金：
中国国家自然科学基金;
关键词：
Traditional Chinese medicines; Quality control markers; Fingerprint-efficacy modeling; Chemometric methods; SPECTRUM-EFFECT RELATIONSHIPS; SUPPORT VECTOR MACHINE; HERBAL MEDICINES; ANTIOXIDANT COMPONENTS; NETWORK PHARMACOLOGY; NATURAL-PRODUCTS; DATA FUSION; CHROMATOGRAPHY; IDENTIFICATION; PREDICTION;
D O I：
10.1016/j.jpba.2018.07.006
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Quality control (QC) is crucial for ensuring the safety and effectiveness of traditional Chinese medicines (TCMs). Due to extremely complicated phytochemical matrices and characteristic mode of "multi-component, multi-target, integrated adjustment", discovering of QC markers from TCMs is a big challenge. Fingerprint-efficacy (FE) modeling method is currently proposed as an effective and reasonable attempt. This review summarizes the methodologies of FE modeling and applications in screening QC markers, meanwhile the future perspectives are also briefly discussed so as to provide inspiration and reference for follow-up study of FE relationship for TCMs. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码：296 / 304
页数：9
相关论文
共 31 条
  • [1] Quality Consistency Evaluation of Traditional Chinese Medicines: Current Status and Future Perspectives
    Liu, Chun-Lu
    Jiang, Yan
    Li, Hui-Jun
    CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, 2024,
  • [2] Efficient Discovery of Quality Control Markers for Gastrodia elata Tuber by Fingerprint-Efficacy Relationship Modelling
    Li, Mingfang
    Du, Yuan
    Wang, Long
    Jiang, Lilong
    Ma, Xiaodong
    Zhou, Ping
    Li, Ping
    Li, Huijun
    PHYTOCHEMICAL ANALYSIS, 2017, 28 (04) : 351 - 359
  • [3] Tentative fingerprint-efficacy study of Houttuynia cordata injection in quality control of traditional chinese medicine
    Lu, Hong-Mei
    Liang, Yi-Zeng
    Wu, Xian-Jin
    Qiu, Ping
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2006, 54 (05) : 725 - 730
  • [4] Chromatographic fingerprint and quality control of traditional Chinese medicines
    Yi Lunzhao
    Wu Hai
    Liang Yizeng
    CHINESE JOURNAL OF CHROMATOGRAPHY, 2008, 26 (02) : 166 - 171
  • [5] Quantification and efficient discovery of quality control markers for Emilia prenanthoidea DC. by Fingerprint-Efficacy Relationship Modelling
    Jiang, Zhengmeng
    Zhao, Chao
    Gong, Xiaojian
    Sun, Xin
    Li, Hongde
    Zhao, Yang
    Zhou, Xin
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 156 : 36 - 44
  • [6] Methods for Quality Control of Fingerprint Chromatograms in Traditional Chinese Medicines
    HU Yuzhu MENG Qinghua LIU Yongsuo JIANG Shumin Department of Analytical Chemistry China Pharmaceutical University Nanjing China
    色谱, 2004, (04) : 361 - 365
  • [7] Current Status and Future Perspective in the Globalization of Traditional Chinese Medicines
    Wan-Ying Wu
    Wen-Zhi Yang
    Jin-Jun Hou
    De-An Guo
    World Journal of Traditional Chinese Medicine, 2015, 1 (01) : 1 - 4
  • [8] Fingerprint-efficacy study of artificial Calculus bovis in quality control of Chinese materia medica
    Kong, Weijun
    Wang, Jiabo
    Zang, Qingce
    Xing, Xiaoyan
    Zhao, Yanling
    Liu, Wei
    Jin, Cheng
    Li, Zulun
    Xiao, Xiaohe
    FOOD CHEMISTRY, 2011, 127 (03) : 1342 - 1347
  • [9] QUALITY CONTROL OF TRADITIONAL CHINESE MEDICINES: INVESTIGATION ON CHEMICAL MARKERS
    Ping Li
    World Journal of Traditional Chinese Medicine, 2015, (04) : 67 - 68
  • [10] Traditional Chinese herbal injection: Current status and future perspectives
    Li, Haona
    Wang, Siwang
    Yue, Zhihua
    Ren, Xuequn
    Xia, Jielai
    FITOTERAPIA, 2018, 129 : 249 - 256
1234