Congenital toxoplasmosis: Should we still care about screening?

被引：9
|
作者：
Petersen, Eskild [1 ,2 ]
Meroni, Valeria [3 ]
Vasconcelos-Santos, Daniel V. [4 ]
Mandelbrot, Laurent [5 ,6 ,7 ,8 ]
Peyron, Francois [9 ]
机构：
[1] Univ Aarhus, Fac Hlth Sci, Inst Clin Med, Aarhus, Denmark
[2] European Soc Clin Microbiol & Infect Dis, Emerging Infect Task Force, Basel, Switzerland
[3] Univ Pavia, Mol Med Dept, Pavia, Italy
[4] Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil
[5] Hop Louis Mourier, AP HP, Serv Gynecol Obstet, Colombes, France
[6] Univ Paris, Paris, France
[7] INSERM, IAME, U1137, Paris, France
[8] FHU PREMA, Paris, France
[9] Hop Croix Rousse, Inst Parasitol & Mycol Med, Lyon, France
来源：
FOOD AND WATERBORNE PARASITOLOGY | 2022年 / 27卷
关键词：
Toxoplasma gondii; Congenital toxoplasmosis; Screening; TO-CHILD TRANSMISSION; PRENATAL TREATMENT; GONDII; RISK; PREGNANCY; RETINOCHOROIDITIS; PREVENTION; INFECTION; INFANTS; IGG;
D O I：
10.1016/j.fawpar.2022.e00162
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Prenatal systematic screening for congenital toxoplasmosis has been performed in Austria and France since 1975 and neonatal screening for congenital toxoplasmosis has been part of the New England Newborn screening program since 1986. In this narrative review we review the data leading up to the systematic screening programs in Austria and France, highlighting the main finding of the European Union funded research in the 1990s and early 2000s. Different descriptive studies of the effect of pre- or postnatal treatment are discussed. Toxoplasma gondii has different genetic lineages with different pathogenicity in humans. This means that results in areas with a low pathogenic lineage cannot be extrapolated to an area with highly pathogenic lineages. The importance of meat as a source of infection is discussed in the light of an increased prevalence of T.gondii in organic livestock production .
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页数：6
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