Transfer reactions catalyzed by cyclodextrin glucosyltransferase using 4-thiomaltosyl and C-maltosyl fluorides as artificial donors

被引：14

作者：

Bornaghi, L

Utille, JP

Rekaï, ED

Mallet, JM

Sinaÿ, P

Driguez, H

机构：

[1] Universite Joseph Fourier, Ctr Rech Macromol Vegetales, CERMAV, CNRS, F-38041 Grenoble 9, France

[2] Ecole Normale Super, Dept Chim, F-75231 Paris, France

来源：

CARBOHYDRATE RESEARCH | 1997年 / 305卷 / 3-4期

关键词：

C-glycosides; S-glycosides; oligosaccharides; enzyme catalysis; enzyme inhibitor;

D O I：

10.1016/S0008-6215(97)00262-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cyclodextrin glycosyltransferase enzyme from Bacillus circulans catalyzed the effective conversion of 4-thio-alpha-maltosyl fluoride into cyclo-alpha-(1-->4)-thiomalto -tetraoside, -pentaoside, -hexaoside and linear hemithiomaltooligosaccharides. However, under the same conditions, C-maltosyl fluoride afforded only linear modified maltotetraose, maltohexaose and maltooctaose in moderate yield. (C) 1997 Elsevier Science Ltd.

引用

页码：561 / 568

页数：8