Role of ascorbic acid and tocopherol in the prevention and treatment of diseases from the standpoint of evidence-based medicine

被引：2

作者：

Shikh, E. V. ^{[1
]}

Makhova, A. A. ^{[1
]}

机构：

[1] IM Sechenov First Moscow State Med Univ, Minist Hlth Russia, Moscow, Russia

来源：

TERAPEVTICHESKII ARKHIV | 2015年 / 87卷 / 04期

关键词：

vitamin C; vitamin E; antioxidants; cytochromes P450; cardiovascular diseases; diabetes mellitus; stroke; induction of metabolic enzymes; VITAMIN-E SUPPLEMENTATION; CORONARY-HEART-DISEASE; CARDIOVASCULAR-DISEASE; ANTIOXIDANT VITAMINS; SECONDARY PREVENTION; RANDOMIZED-TRIALS; WOMENS-HEALTH; ALL-CAUSE; METAANALYSIS; RISK;

D O I：

10.17116/terarkh201587498-102

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The role of vitamin C and vitamin E in the prevention and treatment of diseases is analyzed from the standpoint of evidence-based medicine. The high provision of a patient with the vitamins has a therapeutic and preventive impact on the development and course of a number of diseases. Furthermore, when additionally prescribing the vitamins as part of combination therapy, it is necessary to take into account possible drug interactions, including those due to the inducing effect of the above antioxidants on cytochrome P450 3A4.

引用

页码：98 / 102

页数：5

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