SAMARIUM TRIFLATE-CATALYZED BIGINELLI CONDENSATION: AN IMPROVED METHOD FOR THE SYNTHESIS OF 3,4-DIHYDROPYRIMIDIN-2(1H)-ONES

被引：9
|
作者：
Narsaiah, A. Venkat [1 ]
Reddy, A. Ramesh [1 ]
Yadav, J. S. [1 ]
机构：
[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India
来源：
SYNTHETIC COMMUNICATIONS | 2011年 / 41卷 / 18期
关键词：
Aldehydes; Biginelli reaction; beta-ketoester; Sm(OTf)(3); urea; ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; MULTICOMPONENT REACTIONS; LANTHANUM CHLORIDE; DIHYDROPYRIMIDINONES; EFFICIENT; SYSTEM; UREA;
D O I：
10.1080/00397911.2010.515355
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient method for multicomponant synthesis of 3,4-dihydropyrimidinones has been reported. All the reactions were carried out using samarium triflate as catalyst (10 mol%) at acetonitrile reflux. This procedure is applicable to a variety of substrates such as aliphatic, aromatic, and heterocyclic aldehydes.
引用
收藏
页码：2794 / 2799
页数：6
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