Application of Flow Cytometry in Pediatric Hematology-Oncology

被引：7
|
作者：
Varma, Neelam [1 ]
Naseem, Shano [2 ]
机构：
[1] Postgrad Inst Med Educ & Res, Dept Hematol, Chandigarh 160012, India
[2] Postgrad Inst Med Educ & Res, Div Pediat Hematol, Adv Pediat Ctr, Chandigarh 160012, India
来源：
PEDIATRIC BLOOD & CANCER | 2011年 / 57卷 / 01期
关键词：
acute lymphoblastic leukemia; acute myeloid leukemia; flow cytometry; oncology; pediatric; ACUTE LYMPHOBLASTIC-LEUKEMIA; MINIMAL RESIDUAL DISEASE; HEMATOPOIETIC STEM; PERIPHERAL-BLOOD; BONE-MARROW; CLINICAL-SIGNIFICANCE; GENE REARRANGEMENTS; MRD DETECTION; DNA-PLOIDY; CELLS;
D O I：
10.1002/pbc.22954
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Applications of flow cytometry in pediatric cancers have expanded substantially in recent years. In acute leukemias, the commonest childhood cancer, flow cytometry can now define complex antigenic profiles that are associated with specific cytogenetic/molecular defects and can also directly identify BCR-ABL fusion protein. Flow cytometry based scoring system has been described for diagnosis of myelodysplastic syndromes. In solid tumors, flow cytometry was previously used mainly to determine DNA content for prognosis; however, recent studies in children with neuroblastoma and Ewing sarcoma have identified its diagnostic utility. In this review, we will discuss the current and future applications of flow cytometry in pediatric hematology-oncology. Pediatr Blood Cancer 2011;57:18-29. (C) 2011 Wiley-Liss, Inc.
引用
收藏
页码：18 / 29
页数：12
相关论文
共 50 条
  • [1] Department of pediatric hematology-oncology in Crete
    Kalmanti, M
    [J]. PEDIATRIC HEMATOLOGY AND ONCOLOGY, 1996, 13 (05) : 397 - 399
  • [2] Academic training pathways in pediatric hematology-oncology
    Sakamoto, Kathleen M.
    [J]. PEDIATRIC BLOOD & CANCER, 2006, 47 (03) : 239 - 241
  • [3] Vancomycin use in pediatric hematology-oncology patients
    Hopkins, HA
    Sinkowitz-Cochran, RL
    Rudin, BA
    Keyserling, HL
    Jarvis, WR
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2000, 21 (01): : 48 - 50
  • [4] Establishing a Pediatric Hematology-Oncology Program in Botswana
    Slone, Jeremy S.
    Slone, Amanda K.
    Wally, Oaitse
    Semetsa, Pearl
    Raletshegwana, Mpho
    Alisanski, Susan
    Force, Lisa M.
    Chinyundo, Kamusisi
    Margolin, Judith
    Agrawal, Anurag K.
    Anderson, Alan R.
    Scheurer, Michael E.
    Mehta, Parth S.
    [J]. JOURNAL OF GLOBAL ONCOLOGY, 2018, 4 : 1 - 9
  • [5] Addressing implicit bias in pediatric hematology-oncology
    Tsai, Jessica W.
    Kesselheim, Jennifer C.
    [J]. PEDIATRIC BLOOD & CANCER, 2020, 67 (05)
  • [6] IAP Pediatric Hematology-Oncology Workshop—1999
    [J]. The Indian Journal of Pediatrics, 1999, 66 (1) : 84 - 84
  • [7] Present status of pediatric hematology-oncology in China
    Lu, SG
    Tang, SQ
    [J]. PEDIATRIC HEMATOLOGY AND ONCOLOGY, 1997, 14 (01) : 11 - 15
  • [8] Pediatric hematology-oncology outreach for developing countries
    Wilimas, JA
    Ribeiro, RC
    [J]. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 2001, 15 (04) : 775 - +
  • [9] Invasive aspergillosis in a pediatric hematology-oncology ward
    Lamalmi, F.
    Aghrouch, M.
    Benomar, A.
    Tligui, H.
    Agoumi, A.
    [J]. MEDECINE ET MALADIES INFECTIEUSES, 2012, 42 (06): : 280 - 282
  • [10] Maximizing the Impact of a Pediatric Hematology-Oncology Twinning Program
    Slone, Jeremy S.
    Slone, Amanda K.
    Mehta, Parth S.
    [J]. PEDIATRIC BLOOD & CANCER, 2016, 63 (02) : 369 - 369
12345