共 50 条
Emerging drugs for schizophrenia
被引:18
|作者:
Biedermann, Falko
[1
]
Fleischhacker, W. Wolfgang
[1
]
机构:
[1] Med Univ Innsbruck, Dept Psychiat & Psychotherapy, Clin Biol Psychiat, A-6020 Innsbruck, Austria
关键词:
add-on treatment;
adjunctive treatment;
antipsychotic;
combination treatment;
drug;
mechanism of action;
schizophrenia;
treatment;
PLACEBO-CONTROLLED-TRIAL;
SARCOSINE N-METHYLGLYCINE;
DOPAMINE D-1 RECEPTOR;
DOUBLE-BLIND;
SCHIZOAFFECTIVE DISORDER;
COGNITIVE IMPAIRMENTS;
GALANTAMINE AUGMENTATION;
ADJUNCTIVE TREATMENT;
ANTIPSYCHOTIC-DRUGS;
PSYCHOTIC DISORDERS;
D O I:
10.1517/14728214.2011.556112
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
Areas covered: With the focus on the topics mentioned above, the authors briefly review the latest clinical research organized on the basis of receptor systems and other drug targets, which are discussed to be involved in the pathophysiology of schizophrenia. Expert opinion: In conclusion, although clinicians will have to have considerable patience before truly novel anti-schizophrenia treatments become obtainable, a number of interesting leads with considerable theoretical potential are being explored. As yet, it is difficult to predict which of these mechanisms will effectively augment the currently available treatments.
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页码:271 / 282
页数:12
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