Emerging drugs for schizophrenia

被引:18
|
作者
Biedermann, Falko [1 ]
Fleischhacker, W. Wolfgang [1 ]
机构
[1] Med Univ Innsbruck, Dept Psychiat & Psychotherapy, Clin Biol Psychiat, A-6020 Innsbruck, Austria
关键词
add-on treatment; adjunctive treatment; antipsychotic; combination treatment; drug; mechanism of action; schizophrenia; treatment; PLACEBO-CONTROLLED-TRIAL; SARCOSINE N-METHYLGLYCINE; DOPAMINE D-1 RECEPTOR; DOUBLE-BLIND; SCHIZOAFFECTIVE DISORDER; COGNITIVE IMPAIRMENTS; GALANTAMINE AUGMENTATION; ADJUNCTIVE TREATMENT; ANTIPSYCHOTIC-DRUGS; PSYCHOTIC DISORDERS;
D O I
10.1517/14728214.2011.556112
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Areas covered: With the focus on the topics mentioned above, the authors briefly review the latest clinical research organized on the basis of receptor systems and other drug targets, which are discussed to be involved in the pathophysiology of schizophrenia. Expert opinion: In conclusion, although clinicians will have to have considerable patience before truly novel anti-schizophrenia treatments become obtainable, a number of interesting leads with considerable theoretical potential are being explored. As yet, it is difficult to predict which of these mechanisms will effectively augment the currently available treatments.
引用
收藏
页码:271 / 282
页数:12
相关论文
共 50 条
  • [1] Emerging drugs for schizophrenia
    Agid, Ofer
    Kapur, Shitij
    Remington, Gary
    EXPERT OPINION ON EMERGING DRUGS, 2008, 13 (03) : 479 - 495
  • [2] Emerging drugs for schizophrenia: an update
    Koester, Luisa-Sophie
    Carbon, Maren
    Correll, Christoph U.
    EXPERT OPINION ON EMERGING DRUGS, 2014, 19 (04) : 511 - 531
  • [3] Metabotropic glutamate receptor 5 in schizophrenia: emerging evidence for the development of antipsychotic drugs
    Newell, Kelly A.
    FUTURE MEDICINAL CHEMISTRY, 2013, 5 (13) : 1471 - 1474
  • [4] DRUGS IN SCHIZOPHRENIA
    JANSSEN, PAJ
    BRITISH MEDICAL JOURNAL, 1971, 2 (5754): : 167 - &
  • [5] Emerging Treatments in Schizophrenia
    Correll, Christoph U.
    Abi-Dargham, Anissa
    Howes, Oliver
    JOURNAL OF CLINICAL PSYCHIATRY, 2022, 83 (01)
  • [6] Emerging from schizophrenia
    Cohen, Marvin
    SCHIZOPHRENIA BULLETIN, 2008, 34 (03) : 406 - 407
  • [7] Schizophrenia - An emerging pathophysiology
    Nestler, EJ
    NATURE, 1997, 385 (6617) : 578 - 579
  • [8] Discontinued drugs in 2005: schizophrenia drugs
    Kerwin, Robert
    EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2006, 15 (12) : 1487 - 1495
  • [9] DRUGS, NEUROTRANSMITTERS, AND SCHIZOPHRENIA
    SNYDER, SH
    BANERJEE, SP
    YAMAMURA, HI
    GREENBERG, D
    SCIENCE, 1974, 184 (4143) : 1243 - 1253
  • [10] DRUGS, MEDIATORS AND SCHIZOPHRENIA
    BLANC, M
    RECHERCHE, 1974, 5 (51): : 1096 - 1099