Fomitopsins I and J, 24-methyl-lanostane triterpenoids from fruiting bodies of the wood-rot basidiomycete Fomitopsis sp.

被引：4

作者：

Isaka, Masahiko ^{[1
]}

Chinthanom, Panida ^{[1
]}

Suvannakad, Rapheephat ^{[1
]}

Thummarukcharoen, Tuksaporn ^{[1
]}

Peng, Tao ^{[2
]}

Liu, Ji-Kai ^{[2
]}

机构：

[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, 113 Thailand Sci Pk,Phaholyothin Rd, Klongluang 12120, Pathumthani, Thailand

[2] South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2019年 / 29卷

基金：

中国国家自然科学基金;

关键词：

Fomitopsis; 24-Methyllanostane; Antibacterial activity; LANOSTANE TRITERPENOIDS; FUNGUS; STEROIDS; ACIDS;

D O I：

10.1016/j.phytol.2018.12.006

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new 24-methyl-lanostane triterpenoids, fomitopsins I (1) and J (2), were isolated together with seven known compounds (3-9), from fruiting bodies of the basidiomycete Fomitopsis species. The structures were elucidated by spectroscopic analysis. Their antibacterial and cytotoxic activities were evaluated. One of the known compounds (6) exhibited antibacterial activity against Gram-positive bacteria, Bacillus cereus (MIC 6.25 mu g/ml) and Enterococcus faecium (MIC 12.5 mu g/ml).

引用

页码：178 / 181

页数：4

共 9 条

[1] Lanostane triterpenoids from cultivated fruiting bodies of the wood-rot basidiomycete Ganoderma casuarinicola
Isaka, Masahiko
Chinthanom, Panida
Rachtawee, Pranee
Choowong, Wilunda
Choeyklin, Rattaket
Thummarukcharoen, Tuksaporn
PHYTOCHEMISTRY, 2020, 170
[2] Miscellaneous lanostane triterpenoids with cytotoxicities from fruiting bodies of the basidiomycete Stereum sp.
Yao, Jian-Neng
Chen, Lin
Chen, He-Ping
Zhao, Zhen-Zhu
Zhang, Shuai-Bing
Huang, Ying
Tang, Yang
Isaka, Masahiko
Li, Zheng-Hui
Feng, Tao
Liu, Ji-Kai
FITOTERAPIA, 2018, 125 : 227 - 234
[3] Antimalarial lanostane triterpenoids from cultivated fruiting bodies of the basidiomycete Ganoderma sp.
Masahiko Isaka
Malipan Sappan
Wilunda Choowong
Thitiya Boonpratuang
Rattaket Choeyklin
Tao Feng
Ji-Kai Liu
The Journal of Antibiotics, 2020, 73 : 702 - 710
[4] Antimalarial lanostane triterpenoids from cultivated fruiting bodies of the basidiomycete Ganoderma sp.
Isaka, Masahiko
Sappan, Malipan
Choowong, Wilunda
Boonpratuang, Thitiya
Choeyklin, Rattaket
Feng, Tao
Liu, Ji-Kai
JOURNAL OF ANTIBIOTICS, 2020, 73 (10): : 702 - 710
[5] Lanostane triterpenoids from fruiting bodies of basidiomycete Stereum sp., structures and biological activities
Yao, Jian-Neng
Chen, Lin
Tang, Yang
Chen, He-Ping
Zhao, Zhen-Zhu
Li, Zheng-Hui
Feng, Tao
Liu, Ji-Kai
JOURNAL OF ANTIBIOTICS, 2017, 70 (12): : 1104 - 1111
[6] Lanostane triterpenoids from fruiting bodies of basidiomycete Stereum sp., structures and biological activities
Jian-Neng Yao
Lin Chen
Yang Tang
He-Ping Chen
Zhen-Zhu Zhao
Zheng-Hui Li
Tao Feng
Ji-Kai Liu
The Journal of Antibiotics, 2017, 70 : 1104 - 1111
[7] Highly Modified Lanostane Triterpenes from Fruiting Bodies of the Basidiomycete Tomophagus sp.
Isaka, Masahiko
Chinthanom, Panida
Thummarukcharoen, Tuksaporn
Boonpratuang, Thitiya
Choowong, Wilunda
JOURNAL OF NATURAL PRODUCTS, 2019, 82 (05): : 1165 - 1176
[8] Limonoids from fruiting bodies of the wood-rot basidiomycete Fulvifomes xylocarpicola associated with the mangrove tree Xylocarpus granatum
Isaka, Masahiko
Palasarn, Somporn
Sakayaroj, Jariya
Srichomthong, Kitlada
Nithithanasilp, Sutichai
Sappan, Malipan
PHYTOCHEMISTRY, 2021, 181
[9] Highly Modified Lanostane Triterpenes from the Wood-Rot Basidiomycete Ganoderma colossus: Comparative Chemical Investigations of Natural and Artificially Cultivated Fruiting Bodies and Mycelial Cultures
Isaka, Masahiko
Chinthanom, Panida
Choeyklin, Rattaket
Thummarukcharoen, Tuksaporn
Rachtawee, Pranee
Sappan, Malipan
Srichomthong, Kitlada
Fujii, Ryoma
Kawashima, Kyohei
Mori, Seiji
JOURNAL OF NATURAL PRODUCTS, 2020, 83 (07): : 2066 - 2075

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