Immobilization of nattokinase-loaded red blood cells on the surface of superhydrophobic polypropylene targeting fibrinolytic performance

被引：12

作者：

Li, Chunming ^{[1
,2
]}

Ye, Wei ^{[1
]}

Jin, Jing ^{[1
]}

Xu, Xiaodong ^{[3
]}

Liu, Jingchuan ^{[1
]}

Yin, Jinghua ^{[1
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

[3] Harbin Engn Univ, Coll Mat Sci & Chem Engn, Polymer Mat Res Ctr, Harbin 150001, Peoples R China

来源：

JOURNAL OF MATERIALS CHEMISTRY B | 2015年 / 3卷 / 19期

基金：

美国国家科学基金会;

关键词：

CIRCULATING TUMOR-CELLS; DRUG-DELIVERY; CARRIER ERYTHROCYTES; GRADIENT SURFACES; PLATELET-ADHESION; TOPOGRAPHY; COMPATIBILITY; WETTABILITY; FABRICATION; DEPOSITION;

D O I：

10.1039/c5tb00444f

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

A platform for capture and release of drug-loaded red blood cells (RBCs) is demonstrated by utilizing polymer grafted superhydrophobic polypropylene (PP). Combined with micro/nanobinary structures, thermoresponsive polymers, and lectin-saccharides recognition, this platform enables highly efficient capture and release of RBCs loaded with nattokinase, which endows PP with potent fibrinolytic ability.

引用

页码：3922 / 3926

页数：5

共 7 条

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