Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65

被引：41

作者：

Schultze, Anna ^{[1
]}

Nightingale, Emily ^{[1
]}

Evans, David ^{[2
]}

Hulme, William ^{[2
]}

Rosello, Alicia ^{[1
]}

Bates, Chris ^{[3
]}

Cockburn, Jonathan ^{[3
]}

MacKenna, Brian ^{[2
]}

Curtis, Helen J. ^{[2
]}

Morton, Caroline E. ^{[2
]}

Croker, Richard ^{[2
]}

Bacon, Seb ^{[2
]}

McDonald, Helen, I ^{[1
]}

Rentsch, Christopher T. ^{[1
]}

Bhaskaran, Krishnan ^{[1
]}

Mathur, Rohini ^{[1
]}

Tomlinson, Laurie A. ^{[1
]}

Williamson, Elizabeth J. ^{[1
]}

Forbes, Harriet ^{[1
]}

Tazare, John ^{[1
]}

Grint, Daniel ^{[1
]}

Walker, Alex J. ^{[2
]}

Inglesby, Peter ^{[2
]}

DeVito, Nicholas J. ^{[2
]}

Mehrkar, Amir ^{[2
]}

Hickman, George ^{[2
]}

Davy, Simon ^{[2
]}

Ward, Tom ^{[2
]}

Fisher, Louis ^{[2
]}

Green, Amelia C. A. ^{[2
]}

Wing, Kevin ^{[1
]}

Wong, Angel Y. S. ^{[1
]}

McManus, Robert ^{[3
]}

Parry, John ^{[3
]}

Hester, Frank ^{[3
]}

Harper, Sam ^{[3
]}

Evans, Stephen J. W. ^{[1
]}

Douglas, Ian J. ^{[1
]}

Smeeth, Liam ^{[1
]}

Eggo, Rosalind M. ^{[1
]}

Goldacre, Ben ^{[2
]}

Leon, David A. ^{[1
,4
,5
]}

机构：

[1] London Sch Hyg & Trop Med, Keppel St, London WC1 7HT, England

[2] Univ Oxford, Nuffield Dept Primary Care Hlth Sci, DataLab, Oxford OX2 6GG, England

[3] TPP, TPP House,129 Low Lane, Leeds LS18 5PX, W Yorkshire, England

[4] UiT Arctic Univ Norway, Dept Community Med, Tromso, Norway

[5] Natl Res Univ Higher Sch Econ, Int Lab Populat & Hlth, Moscow, Russia

来源：

LANCET REGIONAL HEALTH-EUROPE | 2022年 / 14卷

基金：

英国科研创新办公室; 英国医学研究理事会; 英国惠康基金;

关键词：

Old Age Homes; Nursing Homes; COVID-19; Mortality; Electronic Health Records; SARS-COV-2; INFECTION; OLDER; OUTBREAKS; COHORT;

D O I：

10.1016/j.lanepe.2021.100295

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Background Residents in care homes have been severely impacted by COVID-19. We describe trends in the mortality risk among residents of care homes compared to private homes. Methods On behalf of NHS England we used OpenSAFELY-TPP to calculate monthly age-standardised risks of death due to all causes and COVID-19 among adults aged >=65 years between 1/2/2019 and 31/03/2021. Care home residents were identified using linkage to Care and Quality Commission data. Findings We included 4,340,648 people aged 65 years or older on the 1st of February 2019, 2.2% of whom were classified as residing in a care or nursing home. Age-standardised mortality risks were approximately 10 times higher among care home residents compared to those in private housing in February 2019: comparative mortality figure (CMF) = 10.59 (95%CI = 9.51, 11.81) among women, and 10.87 (9.93, 11.90) among men. By April 2020 these relative differences had increased to more than 17 times with CMFs of 17.57 (16.43, 18.79) among women and 18.17 (17.22, 19.17) among men. CMFs did not increase during the second wave, despite a rise in the absolute age-standardised COVID-19 mortality risks. Interpretation COVID-19 has had a disproportionate impact on the mortality of care home residents in England compared to older residents of private homes, but only in the first wave. This may be explained by a degree of acquired immunity, improved protective measures or changes in the underlying frailty of the populations. The care home population should be prioritised for measures aimed at controlling COVID-19. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.

引用

页数：13

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