Case-report of a successful pregnancy following thrombolysis for acute myocardial infarction

A non-smoker 24-year-old woman presented to emergency department of Carhaix (France) for evaluation of acute chest pain. She is pregnant since six weeks and has no risk factors for coronary artery disease; her initial electrocardiogram was compatible with an acute posterior myocardial infarction (AMI). After thrombolysis by tenecteplase and treatment with both aspirin and heparin, she underwent coronary and left ventricular angiography that were normal, methergine test involved no coronary spasm. The mechanism of this AMI was not very clear. Nevertheless, an infant is born in good health eight months later after a pregnancy unrolled without any problems (aspirin was stopped at seven months, beta-blocker gradually stopped during second half of pregnancy).