Ixekizumab Associated New-Onset Inflammatory Bowel Disease

被引：8

作者：

Nazarian, Amir ^{[1
]}

Grin, Andrea ^{[2
]}

Wijeratne, Don Thiwanka ^{[1
]}

机构：

[1] Queens Univ, Dept Med, Kingston, ON, Canada

[2] Queens Univ, Dept Pathol, Kingston, ON, Canada

来源：

ACG CASE REPORTS JOURNAL | 2020年 / 7卷 / 02期

关键词：

CELLS;

D O I：

10.14309/crj.0000000000000316

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Ixekizumab is a monoclonal antibody targeting interleukin- 17 approved for the treatment of psoriasis. In a recent post hoc meta-analysis of Phase-I to Phase-III clinical trials of anti-interleukin-17 agents for the treatment of plaque psoriasis, there was a rare association (<1%) with induction or exacerbation of inflammatory bowel disease. We report a case of new-onset ileal Crohn's disease in a 48-year-old woman on ixekizumab for psoriasis.

引用

页数：3

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