Synthesis and biological activity of 7-methyl-3-phenyl-4H-furo [3,2-c] chromen-4-one and 2,7-dimethyl-4H-furo [3,2-c] chromen-4-one and their derivatives

被引：0
|
作者：
Havaldar, FH [1 ]
Bhise, SS [1 ]
机构：
[1] St Xavier Coll, Dept Chem, NSR Lab, Bombay 400001, Maharashtra, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2003年 / 13卷 / 01期
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D O I：
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In a search for new antibacterial agents 7-methyl-3-phenyl-4H-furo [3,2-b]-chromen-4-one (IV) and 2,7-dimethyl-4H-furo [3,2-c] chromen-4-one (VI) have been prepared from substituted 4-hydroxy coumarins by condensing with beta-nitrostyrene and chloroacetone respectively. These products were characterized by UV, IR, PMR & fragmentation pattern of the mass spectra. The compounds have been screened for their antibacterial activity against S. aureus, E coli, B. subtilis and S. typhosa.
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页码：15 / 18
页数：4
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