Drug-related hepatotoxicity and hepatic failure following combined androgen blockade

被引：12
|
作者：
Castro Beza, Inmaculada [1 ]
Sanchez Ruiz, Jesus [1 ]
Peracaula Espino, Francisco Jose [1 ]
Villanego Beltran, M. Isabel [1 ]
机构：
[1] Hosp Punta Europa, Dept Radiat Oncol, ES-11207 Cadiz, Spain
来源：
CLINICAL & TRANSLATIONAL ONCOLOGY | 2008年 / 10卷 / 09期
关键词：
prostate cancer; hormonal therapy; nonsteroidal antiandrogen; drug hepatotoxicity;
D O I：
10.1007/s12094-008-0256-5
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Androgen deprivation therapy has been the mainstay of treatment for metastatic prostate cancer and of less advanced cancers as neoadjuvant and adjuvant treatment. Abnormal liver function test, in particular elevated transaminases, is an adverse reaction more frequently noticed during androgen deprivation therapy with antiandrogen. We report the case of a patient with acute hepatic failure associated with the use of bicalutamide.
引用
收藏
页码：591 / 592
页数：2
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