A disease-modifying strategy for osteoarthritis treatment by intraarticular injection of mRNA encoding cartilage-anabolic transcription factor

被引：0
|
作者：
Itaka, K. [1 ]
Hini, H. [1 ]
Uchida, S. [1 ]
Ohba, S. [1 ]
Chung, U. [1 ]
Kataoka, K. [1 ]
机构：
[1] Univ Tokyo, Tokyo, Japan
来源：
HUMAN GENE THERAPY | 2016年 / 27卷 / 11期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
P335
引用
收藏
页码：A148 / A148
页数：1
相关论文
共 13 条
  • [1] Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment
    Aini, Hailati
    Itaka, Keiji
    Fujisawa, Ayano
    Uchida, Hirokuni
    Uchida, Satoshi
    Fukushima, Shigeto
    Kataoka, Kazunori
    Saito, Taku
    Chung, Ung-il
    Ohba, Shinsuke
    SCIENTIFIC REPORTS, 2016, 6
  • [2] Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment
    Hailati Aini
    Keiji Itaka
    Ayano Fujisawa
    Hirokuni Uchida
    Satoshi Uchida
    Shigeto Fukushima
    Kazunori Kataoka
    Taku Saito
    Ung-il Chung
    Shinsuke Ohba
    Scientific Reports, 6
  • [3] Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor
    Lin, Chin-Yu
    Crowley, Samuel Thomas
    Uchida, Satoshi
    Komaki, Yuji
    Kataoka, Kazunori
    Itaka, Keiji
    MOLECULAR THERAPY-NUCLEIC ACIDS, 2019, 16 : 162 - 171
  • [4] IN SITU MESSENGER RNA DELIVERY OF A CARTILAGE-ANABOLIC TRANSCRIPTION FACTOR USING POLYPLEX NANOMICELLES EXERTS A DISEASE-MODIFYING EFFECT ON OSTEOARTHRITIS
    Aini, H.
    Itaka, K.
    Kataoka, K.
    Saito, T.
    Chung, U-i.
    Ohba, S.
    OSTEOARTHRITIS AND CARTILAGE, 2016, 24 : S27 - S28
  • [5] Raman spectroscopic insight into osteoarthritic cartilage regeneration by mRNA therapeutics encoding cartilage-anabolic transcription factor Runx1
    Pezzotti, Giuseppe
    Zhu, Wenliang
    Terai, Yuki
    Marin, Elia
    Boschetto, Francesco
    Kawamoto, Komei
    Itaka, Keiji
    MATERIALS TODAY BIO, 2022, 13
  • [6] LACTOBACILLUS CASEI L39 AS A POTENTIAL DISEASE-MODIFYING TREATMENT FOR KNEE OSTEOARTHRITIS BY REDUCING INTRAARTICULAR INFLAMMATION
    Waitayangkoon, P.
    Sengprasert, P.
    Sawatpanich, A.
    Yuktanandana, P.
    Ngarmukos, S.
    Tanavalee, A.
    Reantragoon, R.
    OSTEOARTHRITIS AND CARTILAGE, 2020, 28 : S476 - S477
  • [7] LORECIVIVINT (SM04690), A POTENTIAL DISEASE-MODIFYING TREATMENT FOR KNEE OSTEOARTHRITIS, DEMONSTRATED CARTILAGE-PROTECTIVE EFFECTS ON HUMAN OSTEOARTHRITIC EXPLANTS
    Deshmukh, V.
    Grogan, S.
    Seo, T.
    Bhat, D.
    Bugbee, W.
    D'lima, D.
    Yazici, Y.
    ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 : 1331 - 1332
  • [8] LORECIVIVINT (SM04690), A POTENTIAL DISEASE-MODIFYING TREATMENT FOR KNEE OSTEOARTHRITIS, DEMONSTRATED CARTILAGE-PROTECTIVE EFFECTS ON HUMAN OSTEOARTHRITIC EXPLANTS
    Deshmukh, V.
    Grogan, S.
    Seo, T.
    Bhat, D.
    Bugbee, W.
    D'Lima, D.
    Yazici, Y.
    OSTEOARTHRITIS AND CARTILAGE, 2020, 28 : S35 - S36
  • [9] Is detection of disease-modifying osteoarthritis drug treatment more effective when performing cartilage morphometry without blinding to MR image acquisition order?
    Eckstein, Felix
    Wisser, Anna
    Maschek, Susanne
    Wirth, Wolfgang
    Ladel, Christoph
    Bihlet, Asger Reinstrup
    Knight, Chris
    Somberg, Kenneth
    Zhao, Luping
    OSTEOARTHRITIS AND CARTILAGE, 2024, 32 (10) : 1346 - 1351
  • [10] LORECIVIVINT (SM04690), A POTENTIAL DISEASE-MODIFYING TREATMENT FOR KNEE OSTEOARTHRITIS, DEMONSTRATED CARTILAGE-PROTECTIVE EFFECTS ON HUMAN OSTEOARTHRITIC EXPLANTS
    Deshmukh, V.
    Grogan, S.
    Seo, T.
    Bhat, D.
    Bugbee, W.
    D'Lima, D.
    Yazici, Y.
    OSTEOPOROSIS INTERNATIONAL, 2020, 31 (SUPPL 1) : S597 - S598
12