Radiologic and nuclear medicine diagnosis and therapy of thyroid disorders. Part II: Malignant thyroid diseases

被引:0
|
作者
Zechmann, C. M. [1 ]
Haufe, S. [1 ]
机构
[1] Heidelberg Univ, Abt Nukl Med, D-69120 Heidelberg, Germany
来源
RADIOLOGE | 2012年 / 52卷 / 08期
关键词
Thyroid diseases; Thyroid neoplasms; Thyroidectomy; Ablative radioiodine therapy; Redifferentiation; CARCINOMA; SCINTIGRAPHY; PAPILLARY;
D O I
10.1007/s00117-012-2377-1
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Malignant thyroid diseases have increased in recent years. The distinction between differentiated and non-differentiated thyroid carcinoma is essential for therapy and follow-up. The frequently diagnosed papillary and follicular thyroid carcinomas are differentiated and have a good prognosis. Clinical symptoms are relatively unspecific, however imaging and laboratory testing can often provide evidence for diagnosis of thyroid carcinoma. Therapy typically involves surgery, ablative radioiodine therapy and subsequent suppressive hormone substitution. The pillars of follow-up are diagnostic scintigraphy, sonography and laboratory tests. Redifferentiation or a change of the tracer can make dedifferentiated tumors again susceptible to nuclide therapy. New treatment options have become available with the introduction of tyrosine kinase inhibitors.
引用
收藏
页码:761 / 772
页数:12
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