The sandy of microdialysis glucose sensor system based on co-immobilized peroxidase with glucose oxidase by sol-gel technique

被引:0
|
作者
Yu, P [1 ]
Chen, YQ [1 ]
机构
[1] Zhejiang Univ, Dept Biomed Engn, Biosensor Natl Special Lab, Hangzhou 310027, Zhejiang, Peoples R China
关键词
microdialysis; co-enzyme; sol-gel technique;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A microdialysis sensor system for continuous glucose measurements has been developed. The sensor is based on co_immobilzing glucose oxidase (GOD) with the peroxidase on the surface of the silicon bases with Au interdigital electrode using the tetranethoxysilane (TMOS) sol_gel technique. A graduated ("sandwich") immobilizing method is performed to improve the stability and the life time of the co_enzyme system. The result of the optimized co immobilized sensor system demonstrated good agreement between the glucose concentration over the linear range 0.5-50mM and the response time is in the order of less then 2min.
引用
收藏
页码:415 / 416
页数:2
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