A short enantioselective synthesis of the topoisomerase II inhibitor (+)-eleutherin

被引：22
|
作者：
Gibson, Jennifer S. [1 ]
Andrey, Olivier [1 ]
Brimble, Margaret A. [1 ]
机构：
[1] Univ Auckland, Dept Chem, Auckland, New Zealand
来源：
SYNTHESIS-STUTTGART | 2007年 / 17卷 / 17期
关键词：
hauser-Kraus annulation; (+)-eleutherin; pyranonaphthoquinone;
D O I：
10.1055/s-2007-983841
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Hauser-Kraus annulation was used as a key step for the concise enantioselective synthesis of the topoisomerase 11 inhibitor (+)-eleutherin.
引用
收藏
页码：2611 / 2613
页数：3
相关论文
共 50 条
  • [1] A short enantioselective synthesis of (+)-eleutherin, (+)-allo-eleutherin and a formal synthesis of (+)-nocardione B
    Fernandes, Rodney A.
    Chavan, Vijay P.
    Ingle, Arun B.
    TETRAHEDRON LETTERS, 2008, 49 (44) : 6341 - 6343
  • [2] Chemoenzymatic synthesis of deoxy analogues of the DNA topoisomerase II inhibitor eleutherin and the 3C-protease inhibitor thysanone
    Bachu, Prabhakar
    Sperry, Jonathan
    Brimble, Margaret A.
    TETRAHEDRON, 2008, 64 (21) : 4827 - 4834
  • [3] Enantioselective Formal Synthesis of the Cytotoxic Topoisomerase II Inhibitor Deoxythysanone, Catalyzed by Chiral Spiroborate Ester
    M. U. Chopade
    M. D. Nikalje
    H. S. Patil
    A. U. Chopade
    Russian Journal of Organic Chemistry, 2020, 56 : 693 - 697
  • [4] Enantioselective Formal Synthesis of the Cytotoxic Topoisomerase II Inhibitor Deoxythysanone, Catalyzed by Chiral Spiroborate Ester
    Chopade, M. U.
    Nikalje, M. D.
    Patil, H. S.
    Chopade, A. U.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2020, 56 (04) : 693 - 697
  • [5] Synthesis of elenic acid, an inhibitor of topoisomerase II
    J Org Chem, 7 (2450-2453):
  • [6] A synthesis of elenic acid, an inhibitor of topoisomerase II
    Hoye, RC
    Baigorria, AS
    Danielson, ME
    Pragman, AA
    Rajapakse, HA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 217 : U186 - U186
  • [7] Synthesis of elenic acid, an inhibitor of topoisomerase II
    Hoye, RC
    Baigorria, AS
    Danielson, ME
    Pragman, AA
    Rajapakse, HA
    JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (07): : 2450 - 2453
  • [8] Synthesis of elenic acid, an inhibitor of Topoisomerase II.
    Hsung, RP
    Golding, GM
    Johnson, EW
    Pierson, TW
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 219 : U222 - U222
  • [9] SYNTHESIS OF THE TOPOISOMERASE-II INHIBITOR BE-10988
    MOODY, CJ
    SWANN, E
    TETRAHEDRON LETTERS, 1993, 34 (12) : 1987 - 1988
  • [10] First synthesis of subelliptenone F, an inhibitor of topoisomerase II
    Ohira, S
    Fukamachi, N
    Nakagawa, O
    Yamada, M
    Nozaki, H
    Iinuma, M
    CHEMISTRY LETTERS, 2000, (05) : 464 - 465
12345