Multicomponent spectral correlative chromatography applied to analysis of chemical fingerprints of traditional Chinese medicines

被引：0

作者：

Hu, Y ^{[1
]}

Liang, YZ ^{[1
]}

Li, BY ^{[1
]}

Xu, CJ ^{[1
]}

Zeng, ZD ^{[1
]}

机构：

[1] Cent S Univ, Coll Chem & Chem Engn, Res Ctr Modernisat Chinese Herbal Med, Changsha 410083, Peoples R China

来源：

ACTA CHIMICA SINICA | 2003年 / 61卷 / 09期

关键词：

characteristic chemical fingerprint of traditional Chinese medicine (TCM); cluster of chromatographic peaks; hyphenated chromatography; multicomponent spectral correlative chromatography; orthogonal projection technique;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multicomponent spectral correlative chromatography is proposed based on orthogonal projection and correlative chromatography. In order to eliminate the influence of heteroscedastic noise derived from hyphenated instruments, the cosine value of between target component spectrum and its projected residue is applied as a criterion to test the correlative component chromatographic clusters of different chemical fingerprints of traditional Chinese medicines (TCMS). This method provides a practical tool for data processing, reasonable evaluation of chemical fingerprints' of TCMs, and the basic theoretical research on relationship between the chemical fingerprints of TCM and its pharmaceutical efficacy.

引用

页码：1466 / 1470

页数：5

共 10 条

[1] EVOLVING FACTOR-ANALYSIS IN THE PRESENCE OF HETEROSCEDASTIC NOISE
KELLER, HR
MASSART, DL
LIANG, YZ
KVALHEIM, OM
[J]. ANALYTICA CHIMICA ACTA, 1992, 263 (1-2) : 29 - 36
[2] HEURISTIC EVOLVING LATENT PROJECTIONS - RESOLVING 2-WAY MULTICOMPONENT DATA .1. SELECTIVITY, LATENT-PROJECTIVE GRAPH, DATASCOPE, LOCAL RANK, AND UNIQUE RESOLUTION
KVALHEIM, OM
LIANG, YZ
[J]. ANALYTICAL CHEMISTRY, 1992, 64 (08) : 936 - 946
[3] LI BY, IN PRESS CHIN J ANAL
[4] ASSESSMENT OF PEAK ORIGIN AND PURITY IN ONE-DIMENSIONAL CHROMATOGRAPHY BY EXPERIMENTAL-DESIGN AND HEURISTIC EVOLVING LATENT PROJECTIONS
LIANG, YZ
HAMALAINEN, MD
KVALHEIM, OM
ANDERSSON, R
[J]. JOURNAL OF CHROMATOGRAPHY A, 1994, 662 (01) : 113 - 122
[5] LIANG YZ, 1992, ANAL CHEM, V64, P945
[6] Malinowski E.R., 1991, FACTOR ANAL CHEM
[7] SHEN HL, 2000, CHINESE SCI BULL, V45, P587
[8] XIE PS, 2000, CHINESE TRADITIONAL, V22, P391
[9] Chemical rank estimation by noise perturbation in functional principal component analysis
Xu, CJ
Liang, YZ
Li, Y
Du, YP
[J]. ANALYST, 2003, 128 (01) : 75 - 81
[10] Zeng Z, 2003, ACTA CHIM SINICA, V61, P84

← 1 →