The synthesis and determination of acidic ionization constants of certain 5-substituted 2-aminopyrrolo[2,3-d]pyrimidin-4-ones and methylated analogs

被引:12
|
作者
Hoops, GC
Park, J
Garcia, GA
Townsend, LB
机构
[1] Interdepartmental Grad. Prog. M., College of Pharmacy, University of Michigan, Ann Arbor
关键词
D O I
10.1002/jhet.5570330341
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The acidic ionization constants were determined for a series of 5-substituted 2-aminopyrrolo[2,3-dl-pyrimidin-4-ones and N-3- and N-7-methylated analogs thereof. The syntheses of the methylated analogs are also described.
引用
收藏
页码:767 / 781
页数:15
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