Synthesis of 2-alkyl-3-aryl-substituted quinuclidines as novel dopamine transporter inhibitors

被引：9
|
作者：
Sakamuri, S
Enyedy, IJ
Kozikowski, AP
Wang, SM
机构：
[1] Georgetown Univ, Med Ctr, Drug Discovery Program, Washington, DC 20007 USA
[2] Georgetown Univ, Med Ctr, Dept Neurol, Washington, DC 20007 USA
[3] Georgetown Univ, Med Ctr, Dept Oncol, Washington, DC 20007 USA
[4] Georgetown Univ, Med Ctr, Dept Neurosci, Washington, DC 20007 USA
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 51期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S0040-4039(00)01810-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of 2-alkyl-3-aryl-substituted quinuclidines was accomplished in a simple synthetic sequence. The separation of enantiomers was carried out using chiral HPLC. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：9949 / 9952
页数：4
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