Kidney Regenerative Medicine: Promises and Limitations

被引：3

作者：

Frank, Camille Nicolas ^{[1
]}

Petrosyan, Astgik ^{[1
]}

机构：

[1] Childrens Hosp Los Angeles, Saban Res Inst, Div Urol, GOFARR Lab Organ Regenerat Res & Cell Therapeut U, 4650 Sunset Blvd,Mailstop 35, Los Angeles, CA 90027 USA

来源：

CURRENT TRANSPLANTATION REPORTS | 2020年 / 7卷 / 02期

关键词：

Kidney diseases; Renal regenerative medicine; Stem cells; Extracellular vesicles; Xenotransplantation; MESENCHYMAL STEM-CELLS; SYSTEMIC-LUPUS-ERYTHEMATOSUS; PROMOTES RENAL REPAIR; IRREVERSIBLE MODEL; DISEASE; TRANSPLANTATION; SPIRONOLACTONE; FIBROSIS; MUTATION; THERAPY;

D O I：

10.1007/s40472-020-00273-3

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Purpose of Review Advances in renal regenerative medicine are crucial to address the increased rate of kidney disease. Clinicians and researchers are investigating new renal therapeutics aimed at promoting endogenous repair and/or at designing new technologies for organ and tissue regeneration. This review explores the potential promises and limitations of recent renal regenerative medicine approaches. Recent Findings Current research directions include efforts to delay and deter acute and chronic kidney disease progression by exploiting the immune-modulatory and tissue regenerative properties of pharmacology agents, stem cells, and extracellular vesicles. Furthermore, advancement of novel technologies in the field of xenotransplantation, and transplantable devices are showing progress towards the design of de novo replacement organs. With integrated collaborations of multiple disciplinaries, improvements in novel technologies, and understanding of kidney disease progression, the field of renal regenerative medicine is progressing forward with promising therapeutic potential.

引用

页码：81 / 89

页数：9

共 50 条

[1] Kidney Regenerative Medicine: Promises and Limitations
Camille Nicolas Frank
Astgik Petrosyan
[J]. Current Transplantation Reports, 2020, 7 : 81 - 89
[2] Biomaterials in Regenerative Medicine: Promises and Progress
Roeder, Ryan K.
Nychka, John A.
[J]. JOM, 2011, 63 (04) : 49 - 50
[3] Gene transfer into the kidney: Promises and limitations
Kitamura, M
Fine, LG
[J]. KIDNEY INTERNATIONAL, 1997, : S86 - S90
[4] Regenerative Medicine of Liver: Promises, Advances and Challenges
Ali, Saiful
Haque, Nasira
Azhar, Zohya
Saeinasab, Morvarid
Sefat, Farshid
[J]. BIOMIMETICS, 2021, 6 (04)
[5] Regenerative medicine of the kidney
Perin, Laura
Da Sacco, Stefano
De Filippo, Roger E.
[J]. ADVANCED DRUG DELIVERY REVIEWS, 2011, 63 (4-5) : 379 - 387
[6] Regenerative medicine: the promises and perils of a Promethean task Foreword
Moldovan, Nicanor I.
[J]. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2010, 14 (09) : 2189 - 2189
[7] Promises and Challenges of Stem Cell Research for Regenerative Medicine
Power, Carl
Rasko, John E. J.
[J]. ANNALS OF INTERNAL MEDICINE, 2011, 155 (10) : 706 - 713
[8] Regenerative medicine in kidney disease
Little, Melissa H.
Kairath, Pamela
[J]. KIDNEY INTERNATIONAL, 2016, 90 (02) : 289 - 299
[9] Commercialization and regulation of regenerative medicine products: Promises, advances and challenges
Beheshtizadeh, Nima
Gharibshahian, Maliheh
Pazhouhnia, Zahra
Rostami, Mohammadreza
Zangi, Ali Rajabi
Maleki, Reza
Azar, Hanieh Kolahi
Zalouli, Vahideh
Rajavand, Hosnieh
Farzin, Ali
Lotfibakhshaiesh, Nasrin
Sefat, Farshid
Azami, Mahmoud
Webster, Thomas J.
Rezaei, Nima
[J]. BIOMEDICINE & PHARMACOTHERAPY, 2022, 153
[10] Regenerative medicine Kidney injury hope
O'Driscoll, Cath
[J]. CHEMISTRY & INDUSTRY, 2012, 76 (07) : 10 - 10

← 1 2 3 4 5 →