Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate

被引：5
|
作者：
Kochan, Travis J. [1 ]
Ozer, Egon A. [2 ]
Pincus, Nathan B. [1 ]
Fitzpatrick, Margaret A. [3 ]
Hauser, Alan R. [1 ,2 ]
机构：
[1] Northwestern Univ, Feinberg Sch Med, Dept Microbiol Immunol, Chicago, IL 60611 USA
[2] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Infect Dis, Chicago, IL 60611 USA
[3] Loyola Univ Chicago, Stritch Sch Med, Dept Med, Div Infect Dis, Maywood, IL USA
来源：
MICROBIOLOGY RESOURCE ANNOUNCEMENTS | 2020年 / 9卷 / 03期
关键词：
LIVER-ABSCESS; VIRULENCE; CEFOTAXIME; ANNOTATION; RESISTANCE;
D O I：
10.1128/MRA.01408-19
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra-associated conjugation machinery genes. Emergence of conjugative hypervirulence plasmids could portend rapid dissemination of hypervirulence among multidrug-resistant K. pneumoniae strains.
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页数：3
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