Tenofovir, pregnancy and renal function changes in pregnant women living with HIV

被引：5
|
作者：
Thimm, Matthew A. [1 ]
Eke, Ahizechukwu C. [2 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Dept Gynecol & Obstet, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Med, Dept Gynecol & Obstet, Div Maternal Fetal Med & Clin Pharmacol, 600N Wolfe St, Baltimore, MD 21287 USA
来源：
AIDS | 2021年 / 35卷 / 08期
基金：
美国国家卫生研究院;
关键词：
GLOMERULAR-FILTRATION-RATE; DISOPROXIL FUMARATE; REVERSIBILITY;
D O I：
10.1097/QAD.0000000000002880
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
This retrospective study of 100 pregnant women living with HIV [66 on tenofovir disoproxil fumarate (TDF) compared to 34 women on tenofovir alafenamide (TAF)] found no significant difference in renal function in pregnant women with HIV receiving TDF versus TAF. Our results demonstrate that, in regard to renal toxicity, both TDF and TAF appear to be safe for pregnant women living with HIV, but larger prospective cohort studies in pregnant women living with HIV are encouraged.
引用
收藏
页码：1319 / 1320
页数：2
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