Effects of gabapentin on anxiety induced by simulated public speaking

被引：0
|
作者：
de-Paris, F
Sant'Anna, MK
Vianna, MRM
Barichello, T
Busnello, JV
Kapczinski, F
Quevedo, J [1 ]
Izquierdo, I
机构：
[1] Univ Extremo Sul Catarinense, Lab Neurotoxicol, BR-88806000 Criciuma, SC, Brazil
[2] Univ Fed Rio Grande Sul, Ctr Memoria, Dept Bioquim, Inst Ciencias Basicas Saude, Porto Alegre, RS, Brazil
[3] Univ Fed Rio Grande Sul, Grp Psicofarmacol, Dept Psiquiatria, Fac Med, Porto Alegre, RS, Brazil
来源：
JOURNAL OF PSYCHOPHARMACOLOGY | 2003年 / 17卷 / 02期
关键词：
anxiety; jabapentin; simulated public speaking;
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
,The effects of gabapentin, 400 mg and 800 mg, on anxiety induced by simulated public speaking (SPS) were investigated. Thirty-two normal male volunteers (aged 17-30 years) had their anxiety and mood evaluated by self-scales [Visual Analogue. Mood Scale (VAMS) and Profile of Mood State (POMS)], during the SPS procedure. Physiological measures (heart rate and blood pressure) were taken. Treatment with-gabapentin at 800 mg attenuated the anxiety of subjects that had a decrease on the VAMS item calm-excite. In addition, volunteers that received gabapentin at 400 mg and 800 mg showed a decrease in the hostility score in POMS. Our results suggest, in agreement with other studies, an anxiolytic potential to gabapentin.
引用
收藏
页码：184 / 188
页数：5
相关论文
共 50 条
  • [1] Effects of tryptophan depletion on anxiety induced by simulated public speaking
    Monteiro-dos-Santos, PC
    Graeff, FG
    dos-Santos, JE
    Ribeiro, RPP
    Guimaraes, FS
    Zuardi, AW
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2000, 33 (05) : 581 - 587
  • [2] SIMULATED PUBLIC SPEAKING AND ANXIETY
    LIPPER, S
    MCNAIR, DM
    JOURNAL OF EXPERIMENTAL RESEARCH IN PERSONALITY, 1972, 6 (2-3): : 237 - 240
  • [3] Rimonabant effects on anxiety induced by simulated public speaking in healthy humans: a preliminary report
    Bergamaschi, Mateus M.
    Queiroz, Regina H. C.
    Chagas, Marcos H. N.
    Linares, Ila M. P.
    Arrais, Katia C.
    de Oliveira, Danielle C. G.
    Queiroz, Maria E.
    Nardi, Antonio E.
    Huestis, Marilyn A.
    Hallak, Jaime E. C.
    Zuardi, Antonio W.
    Moreira, Fabricio A.
    Crippa, Jose A. S.
    HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 2014, 29 (01) : 94 - 99
  • [4] D-FENFLURAMINE REDUCES ANXIETY INDUCED BY SIMULATED PUBLIC SPEAKING
    HETEM, LAB
    DESOUZA, CJ
    GUIMARAES, FS
    ZUARDI, AW
    GRAEFF, FG
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 1993, 26 (09) : 971 - 974
  • [5] SIMULATED PUBLIC SPEAKING AS A MODEL OF CLINICAL ANXIETY
    MCNAIR, DM
    FRANKENTHALER, LM
    CZERLINSKY, T
    WHITE, TW
    SASSON, S
    FISHER, S
    PSYCHOPHARMACOLOGY, 1982, 77 (01) : 7 - 10
  • [6] Effects of acute cannabidiol administration on anxiety and tremors induced by a Simulated Public Speaking Test in patients with Parkinson's disease
    de Faria, Stephanie Martins
    Fabricio, Daiene de Morais
    Tumas, Vitor
    Castro, Paula Costa
    Ponti, Moacir Antonelli
    Hallak, Jaime E. C.
    Zuardi, Antonio W.
    Crippa, Jose Alexandre S.
    Nisihara Chagas, Marcos Hortes
    JOURNAL OF PSYCHOPHARMACOLOGY, 2020, 34 (02) : 189 - 196
  • [7] Ritanserin facilitates anxiety in a simulated public-speaking paradigm
    Guimaraes, FS
    Mbaya, PS
    Deakin, JFW
    JOURNAL OF PSYCHOPHARMACOLOGY, 1997, 11 (03) : 225 - 231
  • [8] ANXIETY INDUCED BY SIMULATED PUBLIC SPEAKING AND STROOP COLOR-WORD TEST IN HEALTHY-SUBJECTS - EFFECTS OF DIFFERENT TRAIT-ANXIETY LEVELS
    PALMA, SM
    GUIMARAES, FS
    ZUARDI, AW
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 1994, 27 (12) : 2895 - 2902
  • [9] EFFECTS OF PUBLIC SPEAKING ANXIETY ON CARDIAC AWARENESS
    PHILLIPS, GC
    JONES, GE
    RIEGER, EJ
    PSYCHOPHYSIOLOGY, 1995, 32 : S59 - S59
  • [10] Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naive Social Phobia Patients
    Bergamaschi, Mateus M.
    Costa Queiroz, Regina Helena
    Nisihara Chagas, Marcos Hortes
    Gomes de Oliveira, Danielle Chaves
    De Martinis, Bruno Spinosa
    Kapczinski, Flavio
    Quevedo, Joao
    Roesler, Rafael
    Schroeder, Nadja
    Nardi, Antonio E.
    Martin-Santos, Rocio
    Cecilio Hallak, Jaime Eduardo
    Zuardi, Antonio Waldo
    Crippa, Jose Alexandre S.
    NEUROPSYCHOPHARMACOLOGY, 2011, 36 (06) : 1219 - 1226
12345