Efficacy of ofloxacin and other ototopical preparations for chronic suppurative otitis media in children

被引：12
|
作者：
Bluestone, CD
机构：
[1] Childrens Hosp Pittsburgh, Dept Pediat Otolaryngol, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2001年 / 20卷 / 01期
关键词：
ofloxacin; chronic suppurative otitis media; tympanic membrane; perforation;
D O I：
10.1097/00006454-200101000-00040
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The safety and efficacy of ototopical preparations, such as ofloxacin, in the treatment of CSOM in infants and children do not currently have approval by the FDA even though ofloxacin is FDA-approved for treatment of CSOM that occurs in adults. However, treatment with ofloxacin is FDA-approved when AOM occurs in children who have a tympanostomy tube in place, and effective treatment of this acute infection should prevent the subsequent development of CSOM.
引用
收藏
页码：111 / 115
页数：5
相关论文
共 50 条
  • [1] Clinical trial of ototopical ofloxacin for treatment of chronic suppurative otitis media
    Agro, AS
    Garner, ET
    Wright, JW
    de Escobar, IC
    Villeda, B
    Seidlin, M
    CLINICAL THERAPEUTICS, 1998, 20 (04) : 744 - 759
  • [2] Role of glucocorticoids in ototopical antibiotic-steroid preparations in the treatment of chronic suppurative otitis media
    Indudharan, R
    Valuyeetham, KA
    Raju, SS
    ARCHIVES OF MEDICAL RESEARCH, 2005, 36 (02) : 154 - 158
  • [3] Efficacy of ofloxacin and other otic preparations for otitis externa
    Ruben, RJ
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2001, 20 (01) : 108 - 110
  • [4] BACTERIOLOGY OF CHRONIC SUPPURATIVE OTITIS-MEDIA - OFLOXACIN SUSCEPTIBILITY
    YUEN, APW
    CHAU, PY
    WEI, WI
    JOURNAL OF OTOLARYNGOLOGY, 1995, 24 (03): : 206 - 208
  • [5] Efficacy of ofloxacin and other otic preparations for acute otitis media in patients with tympanostomy tubes
    Goldblatt, EL
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2001, 20 (01) : 116 - 119
  • [6] Ototopical drops containing a novel antibacterial synthetic peptide: Safety and efficacy in adults with chronic suppurative otitis media
    Peek, Nanno F. A. W.
    Nell, Marja J.
    Brand, Ronald
    Jansen-Werkhoven, Thekla
    van Hoogdalem, Ewoud J.
    Verrijk, Ruud
    Vonk, Marcel J.
    Wafelman, Amon R.
    Valentijn, A. Rob P. M.
    Frijns, Johan H. M.
    Hiemstra, Pieter S.
    Driphout, Jan W.
    Nibbering, Peter H.
    Grote, Jan J.
    PLOS ONE, 2020, 15 (04):
  • [7] Topical ofloxacin for chronic suppurative otitis media and acute exacerbation of chronic otitis media: Optimum duration of treatment
    Suzuki, K
    Nishimura, T
    Baba, S
    Yanagita, N
    Ishigami, H
    OTOLOGY & NEUROTOLOGY, 2003, 24 (03) : 447 - 452
  • [8] CHRONIC SUPPURATIVE OTITIS-MEDIA IN CHILDREN
    HEUMANN, H
    LARYNGOLOGIE RHINOLOGIE OTOLOGIE VEREINIGT MIT MONATSSCHRIFT FUR OHRENHEILKUNDE, 1987, 66 (01): : 19 - 20
  • [9] Predictors of chronic Suppurative otitis media in children
    van der Veen, Erwin L.
    Schilder, Anne G. M.
    van Heerbeek, Niels
    Verhoeff, Monique
    Zielhuis, Gerhard A.
    Rovers, Maroeska M.
    ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2006, 132 (10) : 1115 - 1118
  • [10] THE EFFICACY OF DOPPLER ULTRASOUND ON CHRONIC SUPPURATIVE OTITIS MEDIA
    Gul, Aylin
    Akdag, Mehmet
    Ozkurt, Fazil Emre
    Aguloglu, Bulent
    Ozkan, Hakan
    Akturk, Adem
    Yilmaz, Beyhan
    ACTA MEDICA MEDITERRANEA, 2015, 31 (01): : 55 - 59
12345