Permeation kinetics of dimethyl sulfoxide in articular cartilage

被引：0
|
作者：
Muldrew, K
Sykes, B
Schachar, N
McGann, LE
机构：
[1] UNIV ALBERTA,DEPT BIOCHEM,EDMONTON,AB T6G 2R7,CANADA
[2] UNIV CALGARY,DEPT SURG,CALGARY,AB,CANADA
来源：
CRYO-LETTERS | 1996年 / 17卷 / 06期
关键词：
cryoprotectant diffusion; tissue cryopreservation; proton NMR; articular cartilage;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
H-1-NMR was used to monitor concentration of dimethyl sulfoxide in articular cartilage on patellae from pigs as a function of time and temperature. The resulting diffusion coefficient was 1.12x10(-5).cm(2)/sec at 23 degrees C with an Arrhenius activation energy of 0.95 kcal/mol. Concentration profiles in cartilage of various thicknesses were calculated as a practical aid for the design of protocols to cryopreserve articular cartilage.
引用
收藏
页码：331 / 340
页数：10
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