Gelatin-based hydrogels for biomedical applications

被引:181
|
作者
Jaipan, Panupong [1 ]
Nguyen, Alexander [2 ,3 ]
Narayan, Roger J. [1 ,2 ,3 ]
机构
[1] North Carolina State Univ, Dept Mat Sci Engn, Box 7907, Raleigh, NC 27695 USA
[2] Univ N Carolina, Joint Dept Biomed Engn, Box 7115, Raleigh, NC 27695 USA
[3] North Carolina State Univ, Box 7115, Raleigh, NC 27695 USA
基金
美国国家卫生研究院;
关键词
MESENCHYMAL STEM-CELLS; CONTROLLED-RELEASE; IN-VITRO; CROSS-LINKING; SCAFFOLDS; FABRICATION; ALGINATE; DESIGN; CARTILAGE; FILMS;
D O I
10.1557/mrc.2017.92
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Gelatin-based hydrogels derived from hydrolysis of collagen have been extensively used in pharmaceutical and medical applications because of their biocompatibility and biodegradability. For example, gelatin-based hydrogels are finding use in drug delivery and tissue engineering because they are able to promote cell adhesion and proliferation. In addition, these hydrogels can be used as wound dressings due to their attractive fluid absorbance properties. Manufacturing technologies such as ultraviolet stereolithography and two-photon polymerization can be used to prepare structures containing photosensitive gelatin-based hydrogels. This review describes the preparation of gelatin-based hydrogels and use of these materials for biomedical applications.
引用
收藏
页码:416 / 426
页数:11
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